跳至主要内容
临床试验/NCT00334217
NCT00334217终止不适用

Cognitive Remediation in the Initial Phase of Substance Abuse Treatment: Feasibility and Efficacy

US Department of Veterans Affairs2 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2005年8月最近更新:
适应症

试验速览

阶段
不适用
状态
终止
入组人数
40
试验地点
2
主要终点
Cognitive improvement and adherence to substance abuse treatment

研究概览

简要总结

This study is for the purpose of determining whether cognitive remediation may improve cognition and treatment response in patients entering substance abuse day treatment

详细描述

Background: Patients entering substance abuse treatment display cognitive deficits that may reduce their ability to benefit from their treatment. While there is considerable variety in the severity and types of cognitive impairment found in newly recovering patients, problems with attention, memory and executive function are very common. Since treatment requires sustained attention, remembering what is learned, integrating that knowledge and applying it to recovery, impairment in underlying cognitive processes makes successful treatment less likely. Although cognitive functioning improves with sustained sobriety, it is during the early phase of recovery that most patients receive the most intensive treatment. Recent research has suggested that cognitive remediation exercises during this early phase may speed up the return of cognitive functioning and in so doing may have a direct effect on whether patients find the treatment useful and complete their treatment. By keeping patients in treatment longer, cognitive remediation may have an indirect effect on substance abuse outcomes.

Objectives: To pilot test the introduction of cognitive remediation at the Substance Abuse Day Treatment Program (SADP) at the Errara Community Care Center. Aims are 1) to assess the receptivity of patients to the intervention by determining rates of agreement to participate, 2) to determine the number of cognitive remediation sessions that patients are willing to engage in, 3) to assess a variety of cognitive remediation tasks for their acceptability, 4) to evaluate neuropsychological improvements using pre-post assessment, 5) to evaluate its effects on substance abuse treatment participation, and 6) to evaluate its effects on substance abuse outcomes at 6 months follow-up.

Design: Randomized clinical trial of cognitive remediation with an active control condition with observations at baseline, end of treatment and 6-months from intake

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Veterans participating in a substance abuse day treatment program at the Errara Community Center

排除标准

  • 未提供

结局指标

主要结局

Cognitive improvement and adherence to substance abuse treatment

时间窗: 6 month follow-up

次要结局

未报告次要终点

研究者

申办方类型
Fed

研究点 (2)

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