Study on the Effect of Selenium Supplementation on the Structure and Function of Autoimmune Thyroiditis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- T1-mapping values of Thyroid MRI
研究概览
简要总结
To evaluate the effects of exogenous selenium supplementation on autoimmune thyroiditis.
详细描述
In patients with autoimmune thyroiditis， investigators compared changes in thyroid function, anti-thyroid peroxidase antibody, anti-thyroglobulin antibody, thyroid magnetic resonance T1-mapping values and metabolic indicatorsfrom baseline to the end of treatment (12 weeks)
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men or women between the ages of 18 and 75
- •Clinical diagnosis of autoimmune thyroiditis, serum TPOAb and TGAB positive
- •Thyroid function is normal, and no drugs affecting thyroid function such as Umetole and Serge have been used
排除标准
- •The contraindications indicated in the Chinese instructions of the drug
- •Hypothyroidism, hyperthyroidism
- •Liver function impairment
- •Renal function impairment
- •Claustrophobia
- •Mental disorders
研究组 & 干预措施
selenium
selenium was administered to patients with autoimmune thyroiditis
干预措施: Selenium (Drug)
结局指标
主要结局
T1-mapping values of Thyroid MRI
时间窗: Changes from baseline and 3 months during follow-up
Changes from baseline and 3 months during follow-up
anti-thyroglobulin antibody changes
时间窗: Changes from baseline and 3 months during follow-up
Changes from baseline and 3 months during follow-up
次要结局
未报告次要终点
研究者
Guang Wang
Professor and Director, Department of Endocrinology
Beijing Chao Yang Hospital