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Selenious acid

Generic Name
Selenious acid
Brand Names
Multitrace-5, Multrys
Drug Type
Small Molecule
Chemical Formula
H2O3Se
CAS Number
7783-00-8
Unique Ingredient Identifier
F6A27P4Q4R

Overview

Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative damage due to peroxides produced during cellular metabolism . Selenium (Se) has been demonstrated to prevent cancer in numerous animal models when administered selenium at levels exceeding the nutritional requirements. One study showed efficacy in the prevention of malignancy while utilizing a selenium supplement in humans. The reports from such studies have heightened the interest in additional human selenium supplementation studies to validate the results in larger populations . Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis .

Background

Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative damage due to peroxides produced during cellular metabolism . Selenium (Se) has been demonstrated to prevent cancer in numerous animal models when administered selenium at levels exceeding the nutritional requirements. One study showed efficacy in the prevention of malignancy while utilizing a selenium supplement in humans. The reports from such studies have heightened the interest in additional human selenium supplementation studies to validate the results in larger populations . Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis .

Indication

Selenium injection is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN). Administration of selenious acid in TPN formulas helps to maintain plasma selenium levels and also to maintain endogenous stores to prevent deficiency . Selenium compounds, such as selenium sulfide, are used topically in anti-dandruff shampoos and in cases of seborrhea . For the purpose of brevity, selenite will the focus of discussion, and more information about selenium can be obtained at Selenium.

Associated Conditions

  • Selenium Deficiency

FDA Approved Products

Vitrexyl
Manufacturer:PureTek Corporation
Route:ORAL
Strength:55 ug in 1 1
Approved: 2023/01/11
NDC:59088-164
Prometa
Manufacturer:PureTek Corporation
Route:ORAL
Strength:70 ug in 1 1
Approved: 2023/02/08
NDC:59088-172
Prenatryl
Manufacturer:PureTek Corporation
Route:ORAL
Strength:70 ug in 1 1
Approved: 2023/02/08
NDC:59088-169
Vitranol Fe
Manufacturer:PureTek Corporation
Route:ORAL
Strength:55 ug in 1 1
Approved: 2023/01/11
NDC:59088-173
Keylosa
Manufacturer:Novian Pharmaceuticals
Route:ORAL
Strength:55 ug in 1 1
Approved: 2023/10/06
NDC:83146-003

Singapore Approved Products

Nutritrace Concentrate for solution for infusion
Manufacturer:B.Braun Melsungen AG
Form:INFUSION, SOLUTION CONCENTRATE
Strength:0.0789mg/10ml
Online:Yes
Approved: 2013/04/22
Approval:SIN14341P
SELENIUM AGUETTANT CONCENTRATE FOR SOLUTION FOR INFUSION 10 MCG/ML
Manufacturer:Laboratoire AGUETTANT
Form:INFUSION, SOLUTION CONCENTRATE
Strength:10 mcg/mL
Online:Yes
Approved: 2023/08/27
Approval:SIN16847P
ADDAVEN CONCENTRATE FOR SOLUTION FOR INFUSION
Manufacturer:Fresenius Kabi Norge AS
Form:INFUSION, SOLUTION CONCENTRATE
Strength:17.29 mcg/ml
Online:Yes
Approved: 2017/07/24
Approval:SIN15302P
PEDITRACE CONCENTRATE FOR PARENTERAL INFUSION
Manufacturer:FRESENIUS KABI NORGE AS
Form:INJECTION
Strength:4.38 mcg/ml
Online:Yes
Approved: 1996/09/04
Approval:SIN08899P

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