T cell-mediated immunity targeting polyomavirus BK
Completed
- Conditions
- BK virus-associated nephropathy / BK virus-associated renal disease100214601004743810029149
- Registration Number
- NL-OMON37893
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 400
Inclusion Criteria
- Being a kidney transplant recipient treated according to the standard treatment protocols applying to kidney transplant recipients treated in the Academic medical Centre Amsterdam.
- Age equal- to or older than eighteen years.
Exclusion Criteria
Age under eighteen years.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Numbers of BKV-specific T cells<br /><br>Phenotype of BKV-specific T cells<br /><br>Functional characteristics of BKV-specific T cells<br /><br>Identification of new epitopes on and in the BKV virion<br /><br>cytokines, chemokines and chemokine receptors in urine</p><br>
- Secondary Outcome Measures
Name Time Method <p>the development of new tetramers through the identification of novel BKV<br /><br>epitopes. </p><br>