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Prospective Clinical trial of BK polyomavirus (BKPyV) infections in adult kidney transplanted patients

Conditions
N14.2
Nephropathy induced by unspecified drug, medicament or biological substance
Registration Number
DRKS00019911
Lead Sponsor
niversitätsmedizin Rostock,Urologische Klinik und Poliklinik
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting withdrawn before recruiting started
Sex
All
Target Recruitment
50
Inclusion Criteria

age at least 18 year
- informed consent
- cadaveric kidney transplantation due to chronic kidney failure

Exclusion Criteria

- multiple organ transplantations

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
- description of BKPyV replication in urine and plasma one year following kidney transplantation as well as infection and retention paraclinics<br>- description of celluar immune response and cytokine release in BKPyV replication<br>- description of virus specific micro-RNA in urine and plasma
Secondary Outcome Measures
NameTimeMethod
- development of an panel of biomarkers for risk assessment in BKPyV infection and development of nephropathy or graft loss
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