Corrected Flow Time in the Carotid Artery as a Predictor of Fluid Responsiveness in Mechanically Ventilated Patients With Low Tidal Volume in the Intensive Care Unit
- Conditions
- Hypovolemic
- Registration Number
- NCT04139031
- Lead Sponsor
- Yonsei University
- Brief Summary
The purpose of this study is to evaluate predictability of carotid corrected flow time for fluid responsiveness in mechanically ventilated patients with low tidal volume in the intensive care unit.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 37
- Adult patients with age more than 19
- Undergoing postoperative mechanical ventilation with low tidal volume
- Clinically diagnosed with hypovolemic status
- If one of follow criteria is satisfied 1) Systolic blood pressure <90mmHg 2) Mean arterial pressure(MBP)<70mmHg or fall more than 20% from baseline 3) Heart rate >100bpm 4) Urine output <0.5mg/kg/hr more than 1 hour 5) Arterial lactate >2mmol/L 6) Capillary refilling time >3secs
- Body mass index <40 or >15 kg/m2
- Medical history of carotid artery stenosis >50% or diagnosed while examination
- Cardiac arrhythmia other than normal sinus rhythm
- Moderate or severe valvular heart disease, intracardiac shunt, heart failure, pulmonary hypertension
- Moderate or severe chronic obstructive pulmonary disease
- Increased intracranial pressure
- Using vasopressor
- Pregnancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Corrected carotid artery flow time during low tidal volume ventilation Procedure (During low tidal volume ventilation before fluid resuscitation) Area under the receiver operating curve of Corrected carotid artery flow time for fluid responsiveness in low tidal volume ventilator setting before fluid resuscitation
- Secondary Outcome Measures
Name Time Method Pulse pressure variation during low tidal volume ventilation Procedure (During low tidal volume ventilation before fluid resuscitation) Area under the receiver operating curve of pulse pressure variation for fluid responsiveness in low tidal volume ventilator setting before fluid resuscitation
Related Research Topics
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Trial Locations
- Locations (1)
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine
🇰🇷Seoul, Korea, Republic of
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine🇰🇷Seoul, Korea, Republic of