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Clinical Trials/NCT04732481
NCT04732481
Completed
Not Applicable

Evaluation of Corrected Carotid Flow Time Variations During Passive Leg Lift to Predict Response to Filling

Centre Hospitalier de Cornouaille1 site in 1 country21 target enrollmentApril 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Organ Failure, Multiple
Sponsor
Centre Hospitalier de Cornouaille
Enrollment
21
Locations
1
Primary Endpoint
response to filling
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Patients hospitalized in intensive care often require intravenous administration of fluid in order to optimize the functioning of the heart and thus ensure perfusion of vital organs such as the kidneys, the brain or the digestive tract. However, it is necessary to find the right balance in fluid intake because it has been shown that excessive administration has a negative impact on patient survival, the length of their stay in intensive care or the duration of invasive mechanical ventilation.The passive leg lifting maneuver is regularly used to determine which patients should be infused with these large volumes (the patient's chest is placed in a horizontal position and the legs are elevated at 30 ° by tilting the bed for 2 minutes ). To be interpreted, this maneuver requires the presence of invasive devices (bloody arterial pressure catheter, PICCO monitor) or an operator experienced in cardiac ultrasound.Our study aims to evaluate an easy-to-use, non-invasive tool widely available in intensive care and emergency departments (carotid vascular doppler ultrasound) to assess the response to a passive leg lifting maneuver. . The measurements are taken before and after a passive leg lifting maneuver and then before and after a filling decided before inclusion by the doctor responsible for the patient.

Registry
clinicaltrials.gov
Start Date
April 1, 2021
End Date
September 1, 2021
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Centre Hospitalier de Cornouaille
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • equipped with a PICCO2® continuous cardiac output monitoring device
  • for which the practitioner in charge of the patient decides to administer a volume expansion

Exclusion Criteria

  • patients whose rhythm is non-sinus
  • who have expressed their refusal to participate in the protocol
  • contraindicated to passive leg lifting maneuvers (deep vein thrombosis, HTIC, BMI\> 40 or\> 14, spinal instability)
  • pregnant women and patients clinically suspected of abdominal compartment syndrome

Outcomes

Primary Outcomes

response to filling

Time Frame: 90sec

Collection of the diagnosis of response to filling after volume expansion of 500mL of Isotonic Salted Serum and evaluation of the variation in TFCc during passive leg lifting between the two groups

Secondary Outcomes

  • cut-off value for positivity of the test(90sec)

Study Sites (1)

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