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临床试验/NCT02843477
NCT02843477已完成不适用

Evaluation of Corrected Carotid Artery Flow Time as a Predictor of Fluid Responsiveness in Spontaneous Breathing Patients

Yonsei University1 个研究点 分布在 1 个国家目标入组 54 人开始时间: 2016年8月9日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
54
试验地点
1
主要终点
ultrasonographic measurement of corrected flow time in carotid artery

研究概览

简要总结

It is still challenging to assess intravascular volume status in spontaneously breathing patients. Recently, the measurement of corrected flow time in carotid artery was introduced as quite useful, simple and noninvasive for the evaluation of circulating blood volume change. The aim of this study is to evaluate whether corrected carotid artery flow time as determined by ultrasonography can be a predictor of fluid responsiveness in spontaneously breathing patients before induction of general anesthesia.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
19 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adult patients (19-80 years of age) who were scheduled to undergo elective neurosurgery for brain tumor

排除标准

  • BMI > 35 or < 15 kg/m2
  • the presence of carotid artery stenosis > 50%
  • systolic blood pressure > 160 mmHg
  • cardiac rhythm other than sinus
  • intracardiac shunt
  • valvular heart disease
  • a left ventricular ejection fraction of < 50%
  • right ventricular dysfunction 9
  • chronic obstructive pulmonary disease
  • pulmonary hypertension
  • chronic kidney disease (eGFR < 60 mL/min/1.73m2)
  • pregnancy

结局指标

主要结局

ultrasonographic measurement of corrected flow time in carotid artery

时间窗: 5 minutes after fluid loading

The ultrasonographic measurement of corrected flow time in carotid artery will be performed 5 minutes after fluid loading.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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