Evaluation of Corrected Carotid Artery Flow Time as a Predictor of Fluid Responsiveness in Spontaneous Breathing Patients

Completed

• Conditions: Brain Tumor
• Interventions: Device: ultrasonographic measurement of corrected flow time in carotid artery

• Registration Number: NCT02843477
• Lead Sponsor: Yonsei University

Brief Summary

It is still challenging to assess intravascular volume status in spontaneously breathing patients. Recently, the measurement of corrected flow time in carotid artery was introduced as quite useful, simple and noninvasive for the evaluation of circulating blood volume change. The aim of this study is to evaluate whether corrected carotid artery flow time as determined by ultrasonography can be a predictor of fluid responsiveness in spontaneously breathing patients before induction of general anesthesia.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-07-21
• Study First Submitted QC: 2016-07-22
• Study First Posted: 2016-07-25
• Study Start: 2016-08-09
• Primary Completion: 2017-02-28
• Study Completion: 2017-02-28
• Status Verified: 2018-07
• Last Update Submitted: 2018-07-15
• Last Update Posted: 2018-07-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

• adult patients (19-80 years of age) who were scheduled to undergo elective neurosurgery for brain tumor

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Exclusion Criteria

• BMI > 35 or < 15 kg/m2
• the presence of carotid artery stenosis > 50%
• systolic blood pressure > 160 mmHg
• cardiac rhythm other than sinus
• intracardiac shunt 6. valvular heart disease
• a left ventricular ejection fraction of < 50%
• right ventricular dysfunction 9
• chronic obstructive pulmonary disease
• pulmonary hypertension
• chronic kidney disease (eGFR < 60 mL/min/1.73m2)
• pregnancy

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Fluid loading group	ultrasonographic measurement of corrected flow time in carotid artery	Spontaneously breathing patients before induction of general anesthesia who receive fluid loading

Primary Outcome Measures

Name	Time	Method
ultrasonographic measurement of corrected flow time in carotid artery	5 minutes after fluid loading	The ultrasonographic measurement of corrected flow time in carotid artery will be performed 5 minutes after fluid loading.

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine; 🇰🇷 Seoul, Korea, Republic of