Inert Gas Rebreathing in Ventilated Patients
- Conditions
- Respiratory FailureHeart FailureSepsisRenal Failure
- Interventions
- Device: non-invasive determination of cardiac output
- Registration Number
- NCT01891253
- Lead Sponsor
- Universitätsmedizin Mannheim
- Brief Summary
Measuring hemodynamic parameters in ventilated patients is important yet still complicated to perform. Inert gas rebreathing (IGR) showed promising results when being compared to other invasive as well as non-invasive techniques for the measurement of cardiac output. The aim of our study is to evaluate the feasibility of IGR in ventilated patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- age 18 - 80 years
- mechanically ventilated patient
- existing PiCCO arterial line
Exclusion Criteria
- FiO2 > 60% (fraction of inspired oxygen)
- PEEP > 10 mmHg (positive end-expiratory pressure)
- SO2 < 90% (oxygen saturation )
- Systolic blood pressure < 90 mmHg
- Heart rate > 150 bpm
- APRV (airway pressure release ventilation)
- ICD (implantable cardioverter defibrillator) / pace maker
- [ Anaesthetic Conserving Device (Anaconda) ]
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description ventilated patients non-invasive determination of cardiac output ventilated patients in an internal medicine ICU with existing PiCCO invasive hemodynamic monitoring
- Primary Outcome Measures
Name Time Method cardiac output 1 day Determination of cardiac output using invasive pulse contour analysis (PiCCO) and non-invasive inert gas rebreathing (Innocor)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Universitätsmedizin Mannheim
🇩🇪Manheim, Baden-Württemberg, Germany