The Effect of Allograft, Toothgraft, Alloplast on Alveolar Ridge Preservation
Overview
- Phase
- Phase 3
- Intervention
- Toothgraft
- Conditions
- Alveolar Ridge Enlargement
- Sponsor
- Ain Shams University
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Clinical assessment
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The primary objective of this study was to compare the efficacy of using allograft, autogenous tooth graft, and beta-tricalcium phosphate for alveolar ridge preservation (ARP) by examining the alveolar ridge height and width at baseline and 3 months after the ARP both clinically and radiographically. The secondary objective was to evaluate the quality of the newly formed bone using histomorphometric analysis.
Detailed Description
This randomized controlled clinical trial included thirty patients. ARP was performed using either Allograft (Allograft group n=10), Tooth graft (Toothgraft group n=10), and beta tri-calcium- phosphate (beta tri-calcium group n=10). Changes in alveolar ridge dimensions were evaluated clinically and radiographically using cone beam computed tomography at baseline and 3 months. Core bone biopsy samples were obtained 3 months post-extraction during implant placement for histomorphometric analysis.
Investigators
Eligibility Criteria
Inclusion Criteria
- •seeking implant-based restorations after tooth extraction.
- •exhibited no evidence of any significant medical history, measured using Burket's Oral medicine health history questionnaire.
- •exhibited Type I and II sockets
Exclusion Criteria
- •nonsmokers.
- •Pregnant and breast-feeding females
- •patients with known contraindications to dental implant surgery (e.g., increased bleeding tendency, history of treatments such as radiotherapy,
Arms & Interventions
Alveolar ridge preservationwith tooth graft
tooth graft
Intervention: Toothgraft
Alveolar ridge preservation with allograft
Allograft
Intervention: Allograft
Alveolar ridge preservation with alloplast
Beta Tri-Calcium phosphate
Intervention: Alloplast
Outcomes
Primary Outcomes
Clinical assessment
Time Frame: 3 months
Bone width loss was calculated by measuring alveolar ridge width buccopalatally in millimeter using a caliper clamp. The measurement was done perpendicular to the tangent of the dental arch at the mid-point of the extraction site approximately 4mm apical to the level of the marginal gingiva of the adjacent teeth.
Secondary Outcomes
- Radiographic assessment(3 months)