The Effect of Allograft, Toothgraft, Alloplast on Alveolar Ridge Preservation
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Clinical assessment
研究概览
简要总结
The primary objective of this study was to compare the efficacy of using allograft, autogenous tooth graft, and beta-tricalcium phosphate for alveolar ridge preservation (ARP) by examining the alveolar ridge height and width at baseline and 3 months after the ARP both clinically and radiographically. The secondary objective was to evaluate the quality of the newly formed bone using histomorphometric analysis.
详细描述
This randomized controlled clinical trial included thirty patients. ARP was performed using either Allograft (Allograft group n=10), Tooth graft (Toothgraft group n=10), and beta tri-calcium- phosphate (beta tri-calcium group n=10). Changes in alveolar ridge dimensions were evaluated clinically and radiographically using cone beam computed tomography at baseline and 3 months. Core bone biopsy samples were obtained 3 months post-extraction during implant placement for histomorphometric analysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •seeking implant-based restorations after tooth extraction.
- •exhibited no evidence of any significant medical history, measured using Burket's Oral medicine health history questionnaire.
- •exhibited Type I and II sockets
排除标准
- •nonsmokers.
- •Pregnant and breast-feeding females
- •patients with known contraindications to dental implant surgery (e.g., increased bleeding tendency, history of treatments such as radiotherapy,
研究组 & 干预措施
Alveolar ridge preservationwith tooth graft
tooth graft
干预措施: Toothgraft (Drug)
Alveolar ridge preservation with allograft
Allograft
干预措施: Allograft (Drug)
Alveolar ridge preservation with alloplast
Beta Tri-Calcium phosphate
干预措施: Alloplast (Drug)
结局指标
主要结局
Clinical assessment
时间窗: 3 months
Bone width loss was calculated by measuring alveolar ridge width buccopalatally in millimeter using a caliper clamp. The measurement was done perpendicular to the tangent of the dental arch at the mid-point of the extraction site approximately 4mm apical to the level of the marginal gingiva of the adjacent teeth.
次要结局
- Radiographic assessment(3 months)