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Clinical Trials/NCT04377178
NCT04377178
Unknown
Not Applicable

Comparison of Autogenous Tooth Graft of Two Different Particle Sizes in Extraction Socket Preservation: A Comparative Clinical and Radiographical Study

SVS Institute of Dental Sciences2 sites in 1 country24 target enrollmentMay 25, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Socket Preservation
Sponsor
SVS Institute of Dental Sciences
Enrollment
24
Locations
2
Primary Endpoint
Bone density
Last Updated
5 years ago

Overview

Brief Summary

The primary objective of the present study is to clinically and radiographically evaluate the efficacy of autogenous tooth graft obtained from bone mill and dental grinder to preserve alveolar ridge dimensions in extraction sockets.

Detailed Description

Accordingly, teeth will be used as a test material to allow for comparative tests after processing it in the automated milling system (AMS). The material will be moistened and then placed in toto into the extraction sockets to generate particles at settings 1 (500 RPM for 30s) or 2 (900 RPM for 30s) to generate MS and SS respectively ((SS group; 0.5-0.8 mm) and medium size (MS group; 1.0-1.2 mm)).

Registry
clinicaltrials.gov
Start Date
May 25, 2019
End Date
December 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr R Viswa Chandra

Primary Investigator

SVS Institute of Dental Sciences

Eligibility Criteria

Inclusion Criteria

  • Systemically healthy individuals within the age group of 20-50 years with presence of teeth with hopeless prognosis requiring extraction

Exclusion Criteria

  • Medically compromised patients.
  • Subjects who underwent radiotherapy or chemotherapy in the past 12 months.
  • Patients having uncontrolled periodontal disease or having an active sinus infection.

Outcomes

Primary Outcomes

Bone density

Time Frame: Baseline to 6months

Radiographs will be taken with digitalized RVG machine (DX 3000, DEXCOWN portable dental X-ray system) at 60Kvp/2Ma with inactive interface. RVG images taken at baseline and 6 months will be utilized to evaluate bone mineral density through Hounsfield units (HU).

Bone fill

Time Frame: Baseline to 6months

The radiograph obtained at 3 and 6 months will be subtracted from the radiograph taken at the baseline by using commercially available image processing software (Adobe Photoshop® 6.0, Adobe Systems, San Jose, USA). After digital subtraction, the digitized and excluded residual bone height will be transferred to open source software for area calculation (ImageJ®, Research Services Branch, NIH, Bethesda, Maryland, USA) for area calculation. The area of the layer will be calculated (in mm2) by initially enclosing the entire area with the rectangular selection tool and then by using Analyze\>Analyze Particles tool.

Study Sites (2)

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