Comparison of plasma concentrations of levobupivacaine with and without epinephrine for thoracic paravertebral block
Not Applicable
- Conditions
- Patients who were scheduled to undergo elective unilateral pulmonary lobectomy or segmentectomy under general anesthesia combined with thoracic paravertebral block for a lung cancer.
- Registration Number
- JPRN-UMIN000021942
- Lead Sponsor
- Wakayama Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients who have contraindication of thoracic paravertebral block. 2)Patients who have allergy to the drugs which will going to use in this trial. 3)Patients who are regarded ineligible by doctors with ather reasons.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The plasma concentration of levobupivacaine was measured at 1, 2.5, 5, 7.5, 10, 12.5, 15, 20, 30, 45, 60, 90, 120 and 150 minutes after paravertebral block. The peak plasma concentration and the time to peak plasma concentration for levobupivacaine were recorded directly from the measured values. The area under the plasma concentration time curve was calculated using the trapezoidal rule.
- Secondary Outcome Measures
Name Time Method Pain:Numerical Rating Scale at rest and at cough after 6,12, 24, 48, and 72 hours postoperation.