Natriuretic Peptides After Left Atrial Appendage Amputation

Not Applicable

Completed

• Conditions: Atrial Fibrillation
• Interventions: Procedure: LAA amputation

• Registration Number: NCT03816410
• Lead Sponsor: University of Giessen

Brief Summary

Surgical amputation of the left atrial appendage (LAA) is an established intervention during surgical atrial fibrillation (AF) therapy. However, its effects on the endocrine function of the left atrium are unclear. This study aims to quantify the serum levels of natriuretic peptides in patients who undergo concomitant surgical AF ablation with or without LAA amputation.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-05-01
• Primary Completion: 2015-10-30
• Study Completion: 2018-12-01
• Status Verified: 2019-01
• Study First Submitted: 2019-01-22
• Study First Submitted QC: 2019-01-22
• Last Update Submitted: 2019-01-22
• Study First Posted: 2019-01-25
• Last Update Posted: 2019-01-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• Indication for concomitant AF therapy during cardiac surgery with cardiopulmonary bypass

Exclusion Criteria

• Lack of informed consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
LAA amputation group	LAA amputation	-

Primary Outcome Measures

Name	Time	Method
Serum levels of proANP and BNP until 800days post surgery	800days

Trial Locations

Locations (1)

Department of Adult and Pediatric Cardiovascular Surgery; 🇩🇪 Giessen, Germany