Dietary Intervention Study to Assess the Effects of Albumin-Derived Peptides on Cardio-Metabolic Risk Factors in Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 69
- 试验地点
- 2
- 主要终点
- A change between baseline blood pressure and endpoint blood pressure within the intervention group vs control group.
研究概览
简要总结
Heart disease and stroke are the most common cause of death in Ireland today.One of the main risk factors for heart disease and stroke is high blood pressure or hypertension. Research has found that certain specific proteins or peptides found in foods such as dairy, meat, fish and eggs may promote heart health reducing blood pressure in adults with hypertension. The aim of this study is to investigate the potential beneficial effects egg peptides may have on heart health, in particular, effects on blood pressure.
详细描述
Poor dietary habits of Irish adults has been accompanied by epidemics of obesity and metabolic disorders such as type II diabetes leading to a substantial predicted increase in the prevalence of chronic diseases such as cardiovascular disease.Hypertension is a major contributing factor to the development of cardiovascular and metabolic diseases. Dietary factors play a significant role in the prevention and/or treatment of hypertension and therefore the development of foods with antihypertensive properties could prove beneficial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male and female
- •Non-diabetic
- •Aged 50-65
- •BMI 25-35kg/m²
- •Mild hypertensive: Blood pressure 130-149 mmHg
排除标准
- •Current smoker
- •Diagnosed hypertensive
- •History of cardiovascular disease
- •Chronic kidney disease
- •Gastrointestinal disease
- •Currently on anti-hypertensive medications
- •Allergic to eggs
结局指标
主要结局
A change between baseline blood pressure and endpoint blood pressure within the intervention group vs control group.
时间窗: 42 days
次要结局
未报告次要终点
研究者
Mairead Kiely PhD
Dr
University College Cork