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Clinical Trials/NCT05454397
NCT05454397
Unknown
N/A

A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients

Nanfang Hospital, Southern Medical University34 sites in 1 country2,000 target enrollmentSeptember 1, 2022
ConditionsAcute Stroke

Overview

Phase
N/A
Intervention
Not specified
Conditions
Acute Stroke
Sponsor
Nanfang Hospital, Southern Medical University
Enrollment
2000
Locations
34
Primary Endpoint
Nutrition compliance rate of stroke inpatients
Last Updated
3 years ago

Overview

Brief Summary

Stroke is the leading cause of premature death and disability, and early recognition and treatment of dysphagia is fundamental to stroke management. Early and full tube feeding in the acute phase of stroke helps to address nutritional problems resulting from dysphagia and impaired consciousness and helps to reduce morbidity and mortality and poor outcomes. Current guidelines for acute stroke management do not address the goal of tube feeding of enteral nutrition for energy and protein. In the treatment of acute stroke, there is a strong global focus on pharmacological thrombolysis or mechanical thrombolysis, with nutritional interventions being a less explored topic. Real-world evidence on large samples, feeding attainment and outcomes, and nutrition in the acute phase of stroke is lacking in China . The aim of this study was to understand the current status of nutritional therapy in stroke hospitalization in neurology and its impact on prognosis nationwide, and to improve the standardized management process of enteral nutrition therapy in the acute phase of stroke.

Detailed Description

Malnutrition is a common geriatric syndrome with a disproportionate incidence in geriatric and neurology inpatients. In recent years, national nutritional surveys of geriatric inpatients have shown that about 2/3 of geriatric inpatients have nutritional problems; only half of neurology inpatients at high risk receive nutritional support, and inadequate nutrition exacerbates primary disease, increases complications, makes hospital stays longer, and ultimately affects patient survival outcomes. To increase comprehensive and up-to-date research on the current status of nutritional therapy in geriatric and neurology inpatients, and to lay the foundation for future standardized treatment and standardized management, we conducted a nationwide survey on the current status of nutritional risk screening and treatment in geriatric and neurology inpatients. The aim is to raise the level of clinicians' awareness of malnutrition and nutritional risk in hospitalized patients, standardize clinical practice, and properly implement nutritional support to improve patients' clinical outcomes.

Registry
clinicaltrials.gov
Start Date
September 1, 2022
End Date
October 15, 2023
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Newly admitted stroke patients admitted to neurology, age ≥18 years, within 7 days of onset, expected survival \>3 months (i.e., not end-stage), expected neurology stay 7-10 days;
  • At risk of malnutrition (MUST ≥ 2 points) or at nutritional risk (NRS2002 ≥ 3 points), sign an informed notice.

Exclusion Criteria

  • Transferred during treatment, contraindications to nutritional therapy (e.g., hemodynamic instability, gastrointestinal bleeding (bleeding \>100 ml), other nutritional studies, pregnancy.

Outcomes

Primary Outcomes

Nutrition compliance rate of stroke inpatients

Time Frame: The first day of admission; the seventh day of admission; the day before discharge.

Percentage of patients hospitalized for stroke whose nutritional indicators and nutritional status met the guidelines after being given nutritional support

Nutrition implementation rate

Time Frame: The first day of admission; the seventh day of admission; the day before discharge.

Proportion of patients hospitalized for stroke who were given nutritional support

Secondary Outcomes

  • Infection rate(30-day post-discharge)
  • Functional prognosis(30-day post-discharge)
  • 30-day post-discharge mortality(30-day post-discharge)
  • Readmission rate(30-day post-discharge)

Study Sites (34)

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