Investigation of the Efficacies of Multi Berries Juice on Anti Oxidant Effect and Improvement of Skin Conditions

Not Applicable

Completed

• Conditions: Skin Condition; Anti Oxidative Stress
• Interventions: Dietary Supplement: multi berries juice; Dietary Supplement: Placebo drink

• Registration Number: NCT04878523
• Lead Sponsor: TCI Co., Ltd.

Brief Summary

To assess multi berries juice on anti-oxidant effect and skin condition improvement

Detailed Description

Not available

Study Timeline

• Study Start: 2020-11-09
• Primary Completion: 2021-01-15
• Study Completion: 2021-02-25
• Status Verified: 2021-05
• Study First Submitted: 2021-05-06
• Study First Submitted QC: 2021-05-06
• Last Update Submitted: 2021-05-06
• Study First Posted: 2021-05-07
• Last Update Posted: 2021-05-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Healthy adults aged above 20 years old

Exclusion Criteria

• Subject who is not willing to participate in this study.
• Patients with diseases of the skin, liver, kidney.
• Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
• Constant drug use

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
multi berries juice	multi berries juice	-
Placebo drink	Placebo drink	-

Primary Outcome Measures

Name	Time	Method
The change of skin UV spots	Change from Baseline skin UV spots at 8 weeks	VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units
The change of skin melanin index	Change from Baseline skin melanin index at 8 weeks	Soft Plus was utilized to measure skin melanin index. Units: arbitrary units
The change of blood SOD content	Change from Baseline SOD content at 8 weeks	Venous blood was sampled to measure concentrations of SOD
The change of blood total antioxidant capacity (TAC)	Change from Baseline TAC at 8 weeks	Venous blood was sampled to measure concentrations of TAC
The change of skin L* value	Change from Baseline L* value at 8 weeks	Chroma Meter MM500 was utilized to measure skin L\* value. Units: arbitrary units, 0-100
The change of skin spots	Change from Baseline skin spots at 8 weeks	VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units
The change of skin brown spots	Change from Baseline skin brown spots at 8 weeks	VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units

Secondary Outcome Measures

Name	Time	Method
The change of skin moisture	Change from Baseline skin moisture at 4 weeks	Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120
The change of skin a* value	Change from Baseline a* value at 8 weeks	Chroma Meter MM500 was utilized to measure skin a\* value. Units: arbitrary units
The change of skin elasticity	Change from Baseline skin elasticity at 8 weeks	Soft Plus was utilized to measure skin elasticity. Units: arbitrary units
The change of skin wrinkles	Change from Baseline skin wrinkles at 8 weeks	VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units
The change of skin texture	Change from Baseline skin texture at 8 weeks	VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of skin collagen density	Change from Baseline skin collagen density at 8 weeks	DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units
The change of skin pores	Change from Baseline skin pores at 8 weeks	VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units

Trial Locations

Locations (1)

Chia Nan University of Pharmacy & Science; 🇨🇳 Tainan City, Taiwan