Metabolic and Endocrinological Characterization of a Prospective Cohort of Women With PCOS
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- bone mass density (BMD)
研究概览
简要总结
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women. PCOS is characterized by increase levels of testosterone, unwanted hair growth, adiposity, irregular menstrual cycle, and infertility. PCOS is associated with diabetes mellitus and cardiovascular diseases. Women with PCOS are reported to have increased levels of stress hormones, which may be associated with decreased quality of life. Increased testosterone levels in women may decrease the risk of osteoporosis. The aim of the present study is to measure levels of stress hormones in urine and describe quality of life using questionnaires. In addition we aim to characterize body composition and bone architecture using DXA and ExtremeCT.
As part of the project, a Biobank with fasting blood samples from participants is established.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •pregnancy
结局指标
主要结局
bone mass density (BMD)
时间窗: baseline
BMD measured by DXA scans and ExtremeCT scans.
次要结局
- Stress hormones(Baseline)
研究者
Marianne Andersen
DMSci
Odense University Hospital