Glucose Metabolism, Adrenal Function, Cortisol Metabolism, Body Composition Physical Activity, and Quality of Life in Healthy Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Level of androgens
研究概览
简要总结
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women. Women with PCOS often have problems with fertility, unwanted hair growth, and irregular menstrual cycle. PCOS is associated with obesity, changes in glucose metabolism and low quality of life.
In the present study, hormonal profile, glucose metabolism, adrenal functon, androgen levels, cortisol metabolism, anflammatory response, ovarian morphology, body composition, pfysical activity and quality of life is studied in 40 healthy women. The results will be compared with results from studies on women with PCOS in order to investigate any differences in these parametres.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •No medications
- •regular menstrual cycle
- •no hair growth problems
- •BMI 18-35 kg/m2
排除标准
- •medication
- •diabetes mellitus
- •signs of PCOS
- •BMI < 18 or > 35
结局指标
主要结局
Level of androgens
时间窗: baseline
Level of testosterone and sexual hormone binding globuline in blood samples
次要结局
- Body composition(baseline)
- Bone density(baseline)
- Glucose tolerance(5 hours)
- Quality of life(Baseline)
研究者
Marianne Andersen
DMSci
Odense University Hospital