Glucose Metabolism, Adrenal Function, Cortisol Metabolism, Body Composition Physical Activity, and Quality of Life in Healthy Women
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy
- Sponsor
- Odense University Hospital
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Level of androgens
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women. Women with PCOS often have problems with fertility, unwanted hair growth, and irregular menstrual cycle. PCOS is associated with obesity, changes in glucose metabolism and low quality of life.
In the present study, hormonal profile, glucose metabolism, adrenal functon, androgen levels, cortisol metabolism, anflammatory response, ovarian morphology, body composition, pfysical activity and quality of life is studied in 40 healthy women. The results will be compared with results from studies on women with PCOS in order to investigate any differences in these parametres.
Investigators
Marianne Andersen
DMSci
Odense University Hospital
Eligibility Criteria
Inclusion Criteria
- •No medications
- •regular menstrual cycle
- •no hair growth problems
- •BMI 18-35 kg/m2
Exclusion Criteria
- •medication
- •diabetes mellitus
- •signs of PCOS
- •BMI \< 18 or \> 35
Outcomes
Primary Outcomes
Level of androgens
Time Frame: baseline
Level of testosterone and sexual hormone binding globuline in blood samples
Secondary Outcomes
- Body composition(baseline)
- Bone density(baseline)
- Glucose tolerance(5 hours)
- Quality of life(Baseline)