The Study of Metabolic and Cardiac Vascular Risk in Patients With Polycystic Ovary Syndrome
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Polycystic Ovary Syndrome
- Sponsor
- Taipei Medical University WanFang Hospital
- Enrollment
- 169
- Locations
- 1
- Primary Endpoint
- The correlation of PCOS betwwen metabolic and cardiovascular disease.
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Polycystic ovary syndrome (PCOS) is an extremely common disorder in women of reproductive age. Diagnosis of PCOS is principally based on clinical and physical findings. Diagnostic criteria and PCOS definitions used by clinicians and researchers are almost as heterogeneous as the syndrome. This first part of study is determine whether genetic polymorphisms influence hormonal and metabolic characteristics in Taiwanese patients with PCOS and controls. Furthermore, women with PCOS were reported with high risk of cardiovascular disease, the investigators planned to calculate the difference of carotid intima-media thickness (IMT) and B-type natriuretic peptide (BNP) between women with PCOS and normal control to determine the premature atherosclerosis of women with PCOS.
Investigators
Ming-I Hsu, MD
Attending Doctor
Taipei Medical University WanFang Hospital
Eligibility Criteria
Inclusion Criteria
- •women at reproductive age
- •women with PCOS and women without PCOS.
Exclusion Criteria
- •young women who had their menarche less than 3 years
- •women older than 45 years old, Amenorrhea of menopause, hyperglycemia, hyperthyroidism, hypothyroidism, heart failure, lung failure, renal failure, anemia, dystrophy, gonitis.
Outcomes
Primary Outcomes
The correlation of PCOS betwwen metabolic and cardiovascular disease.
Time Frame: Participant were followed for 1 month in study period.