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临床试验/NCT01392781
NCT01392781Unknown不适用

Markers and Calculation of Cardiovascular Risk in the Distinct Phenotypes of Polycystic Ovary Syndrome

Aristotle University Of Thessaloniki1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2011年4月最近更新:
适应症

试验速览

阶段
不适用
入组人数
300
试验地点
1
主要终点
high sensitivity C-Reactive Protein (hsC-RP) levels and differences between the phenotypes

研究概览

简要总结

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder and cause of anovulatory infertility among reproductive aged women. According to the revised criteria of 2003, four distinct phenotypes of PCOS can be diagnosed. However, there are emerging evidence supporting the existence of different levels of cardiometabolic risk between the four phenotypic groups of the syndrome. The purpose of this study is to determine the cardiovascular risk of i) normoweight and ii)overweight plus obese women of every one of the four phenotypes of the syndrome as well as the levels of low inflammation serum markers and the possible correlations of the between the outcomes.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
15 Years 至 35 Years(Child, Adult)
性别
Female
接受健康志愿者

入选标准

  • Diagnosis of PCOS (criteria 2003)
  • Healthy controls

排除标准

  • any condition mimicking PCOS
  • any systematic disease

结局指标

主要结局

high sensitivity C-Reactive Protein (hsC-RP) levels and differences between the phenotypes

时间窗: 1 hour

Cardiovascular Risk Assessment and differences between the phenotypes

时间窗: 1 hour

Lipoprotein-associated phospholipase2 (Lp-PLA2) levels and differences between the phenotypes

时间窗: 1 hour

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (1)

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