Markers and Calculation of Cardiovascular Risk in the Distinct Phenotypes of Polycystic Ovary Syndrome
试验速览
- 阶段
- 不适用
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- high sensitivity C-Reactive Protein (hsC-RP) levels and differences between the phenotypes
研究概览
简要总结
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder and cause of anovulatory infertility among reproductive aged women. According to the revised criteria of 2003, four distinct phenotypes of PCOS can be diagnosed. However, there are emerging evidence supporting the existence of different levels of cardiometabolic risk between the four phenotypic groups of the syndrome. The purpose of this study is to determine the cardiovascular risk of i) normoweight and ii)overweight plus obese women of every one of the four phenotypes of the syndrome as well as the levels of low inflammation serum markers and the possible correlations of the between the outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 35 Years(Child, Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Diagnosis of PCOS (criteria 2003)
- •Healthy controls
排除标准
- •any condition mimicking PCOS
- •any systematic disease
结局指标
主要结局
high sensitivity C-Reactive Protein (hsC-RP) levels and differences between the phenotypes
时间窗: 1 hour
Cardiovascular Risk Assessment and differences between the phenotypes
时间窗: 1 hour
Lipoprotein-associated phospholipase2 (Lp-PLA2) levels and differences between the phenotypes
时间窗: 1 hour
次要结局
未报告次要终点
