The Study of Polycystic Ovary Syndrome (PCOS) and Questionnaire
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Polycystic Ovary Syndrome
- Sponsor
- Taipei Medical University WanFang Hospital
- Enrollment
- 306
- Locations
- 1
- Primary Endpoint
- Obesity is the predominant predictor of impaired glucose tolerance and metabolic disturbance in polycystic ovary syndrome.
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Polycystic ovary syndrome (PCOS) is an extremely common disorder in women of reproductive age. Diagnosis of PCOS is principally based on clinical and physical findings. Diagnostic criteria and PCOS definitions used by clinicians and researchers are almost as heterogeneous as the syndrome. This first part of study is determine whether genetic polymorphisms influence hormonal and metabolic characteristics in Taiwanese patients with PCOS and controls. Furthermore, women with PCOS were reported with high risk of cardiovascular disease, the investigators planned to calculate the difference of carotid intima-media thickness (IMT) and B-type natriuretic peptide (BNP) between women with PCOS and normal control to determine the premature atherosclerosis of women with PCOS.
Investigators
Ming-I Hsu
Attending Doctor
Taipei Medical University WanFang Hospital
Eligibility Criteria
Inclusion Criteria
- •women at reproductive age
- •women with PCOS and women without PCOS
Exclusion Criteria
- •young women who had their menarche less than 3 years
- •women older than 45 years old, Amenorrhea of menopause, hyperglycemia, hyperthyroidism, hypothyroidism, heart failure, lung failure, renal failure, anemia, dystrophy, gonitis
Outcomes
Primary Outcomes
Obesity is the predominant predictor of impaired glucose tolerance and metabolic disturbance in polycystic ovary syndrome.
Time Frame: Prospectively study in University teaching hospital from 31 August 2010 to 31 August 2011.
To evaluate the contribution to glucose intolerance and metabolic syndrome of obesity combined with the diagnostic criteria of polycystic ovary syndrome (PCOS).