Clonidine and Buprenorphine in treatment of Opioid Addiction.
- Conditions
- Health Condition 1: null- Opioid dependence
- Registration Number
- CTRI/2016/03/006766
- Lead Sponsor
- Government Medical College Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
1.)Male subjects of age 18-60 years.
2.)Patient should be willing for admission.
3.)Patient willing to give urine sample for opioid screening on demand.
4.)In case of co morbid mental disorder patient should be clinically stable i.e. there has been no change in medication or increase in dose by 50% in last 3 month.
5.)Patient willing to participate in the study.
1.)Patient with co morbid medical/surgical illness in which clonidine and buprenorphine is contraindicated.
2.)Patient with other substance dependence except for nicotine or caffeine.
3.)Patient with evidence of sub-normal intelligence or active major mental disorder which cause cognitive decline.
4.)Subjects who have been on opioid maintenance.
5.)Subjects reporting after 48 hours of last use of opioid.
6.)Actively suicidal patient.
7.)History of any adverse drug reaction with buprenorphine and clonidine in the past
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method