A prospective comparative evaluation of dysphagia in surgically resected oral cavity cancers treated by dysphagia optimized volumetric modulated arc therapy (Do-VMAT) versus standard volumetric modulated arc therapy (S-VMAT)

Homi Bhabha Cancer Hospital And Mahamana Pandit Madan Mohan Malaviya Cancer Centre0 个研究点目标入组 0 人开始时间: 待定最近更新: 2022年10月17日

试验速览

暂无简介。

•Histologically proven squamous cell carcinoma of oral cavity (excluding lip)
•Written informed consent
•Age - 18 to 70 years
•Karnofsky performance status 70 or above
•Adequate surgical resection of primary and nodal diseas
•Non-metastatic disease
•Patients planned for adjuvant chemo-radiation only (Extra capsular extension +ve, Margin +ve or patients receiving NACT prior to surgery)
•Only patients taking intake orally at the time of start of radiation will be included

•1.Any histopathology other than SCC
•2.Previous radiotherapy to the head and neck region
•3.Synchronous or metachronous malignancy
•4.Pregnant or lactating women
•5.Uncontrolled concurrent illness like Diabetes mellitus (DM), Hypertension (HTN), tuberculosis
•6.Evidence of distant metastasis
•7.Recurrent or residual disease.
•8.Current or previous tracheostomy placement.
•9.Posterior pharyngeal wall, post cricoid and retro pharyngeal lymph node involvement
•10.Patients on Ryles tube feeding at the time of RT start will be excluded.

发起方

Homi Bhabha Cancer Hospital And Mahamana Pandit Madan Mohan Malaviya Cancer Centre