CTRI/2022/08/044696
Not yet recruiting
未知
A prospective comparative evaluation of dysphagia in surgically resected oral cavity cancers treated by dysphagia optimized volumetric modulated arc therapy (Do-VMAT) versus standard volumetric modulated arc therapy (S-VMAT)
Homi Bhabha Cancer Hospital And Mahamana Pandit Madan Mohan Malaviya Cancer Centre0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: C04- Malignant neoplasm of floor of mouthHealth Condition 2: C03- Malignant neoplasm of gumHealth Condition 3: C06- Malignant neoplasm of other and unspecified parts of mouthHealth Condition 4: C02- Malignant neoplasm of other and unspecified parts of tongue
- Sponsor
- Homi Bhabha Cancer Hospital And Mahamana Pandit Madan Mohan Malaviya Cancer Centre
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Histologically proven squamous cell carcinoma of oral cavity (excluding lip)
- •Written informed consent
- •Age \- 18 to 70 years
- •Karnofsky performance status 70 or above
- •Adequate surgical resection of primary and nodal diseas
- •Non\-metastatic disease
- •Patients planned for adjuvant chemo\-radiation only (Extra capsular extension \+ve, Margin \+ve or patients receiving NACT prior to surgery)
- •Only patients taking intake orally at the time of start of radiation will be included
Exclusion Criteria
- •1\.Any histopathology other than SCC
- •2\.Previous radiotherapy to the head and neck region
- •3\.Synchronous or metachronous malignancy
- •4\.Pregnant or lactating women
- •5\.Uncontrolled concurrent illness like Diabetes mellitus (DM), Hypertension (HTN), tuberculosis
- •6\.Evidence of distant metastasis
- •7\.Recurrent or residual disease.
- •8\.Current or previous tracheostomy placement.
- •9\.Posterior pharyngeal wall, post cricoid and retro pharyngeal lymph node involvement
- •10\.Patients on Ryles tube feeding at the time of RT start will be excluded.
Outcomes
Primary Outcomes
Not specified
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