onlinear respiratory mechanics during mechanical ventilation in patientsundergoing cardiac surgery
Not Applicable
- Conditions
- Patients with cardiosurgical proceddure including 1-2h of HLM use, e.g. aortocoronary bypass operations or aortic valve operations
- Registration Number
- DRKS00033071
- Lead Sponsor
- niversitätsklinikum Freiburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 114
Inclusion Criteria
Elektiv cardial surgery OP with sternotomy and clamping of the aorta.
ASA status < V
written informed consend
Exclusion Criteria
pregnancy, case of emergency, increased risk of aspiration, treated pneumonia, GOPD GOLD = 4, Language barrier excluding informed consent. Cases in which surgery time is prolonged > 60 min or require stop of lung ventilation > 10 min in the ventilation group for surgical reasons will be excluded from data analyses.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of nonlinear respiratory system compliance between start and end of surgical procedure. Calculations will be based on the pressure and flow curves, measured at the ventilator.
- Secondary Outcome Measures
Name Time Method Frequency of intraoperative compliance profiles, frequencies of postoperative pulmonary complications (O2 required, atelectasis, pneumonia), vitalparameters of monitoring: ECG, arterial blood pressures, paO2, paCO2, SaO2, etCO2 in course.