NL-OMON44786已完成不适用
*Energetics in hypertrophic cardiomyopathy: translation between PET, MRI and cardiac myofilament function* - 'ENGINE'-study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •HOCM-patients scheduled for classic myectomy and eligible for CMR-and PET imaging. Indication for myectomy was based on a significant LV outflow tract (LVOT) pressure gradient >=30 mmHg at rest or provoked as documented by echocardiography and symptoms, despite optimal medical treatment.
- •Aortic valve stenosis patients selected to undergo valve surgery, according to the ESC-guidelines on the management of valvular heart disease.
- •Non-hypertrophic carriers (NHC) eligible for CMR- and PET imaging;Ref. Vahanian A et al. Guidelines on the management of valvular heart disease: The Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology. Eur Heart J. 2007 Jan;28(2):230-68. ;Protocol page 11-12
排除标准
- •Any absolute or relative contra-indication for CMR imaging (i.e. pacemaker and claustrophobia) or failure to give informed consent. Severely impaired renal function with a glomerular filtration rate (GFR) <30 ml/min.
- •Protocol page 11-12
研究者
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