Evaluation of the Clinical Effect of the Formulation of Individualized Exercise Prescription for Hypertension With 6-minute Walking Test (6MWT)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 126
- 主要终点
- PWV
研究概览
简要总结
Obesity and lack of exercise are one of the reasons for high blood pressure. Exercise can reduce the risk of cardiovascular events by reducing weight and blood pressure. The precise formulation of exercise prescription by cardiopulmonary exercise test (CPET) can effectively control hypertension. Our research group has formulated 50 "exercise prescriptions for hypertension population" in the early stage, but how to further effectively implement them needs to be discussed.
Based on the previous experience of undertaking the project "Exercise Prescription for Hypertensive People" of General Administration of Sport of the People's Republic of China, this research group discussed the important role of intelligent information management in the clinical effect evaluation and effective implementation of exercise prescription for hypertension; To explore the feasibility of making exercise prescription for hypertension based on 6-min walking test, and whether it is not inferior to or equivalent to the accuracy and effectiveness of making exercise prescription by CPET. The relevant results will lay a foundation for exploring the broader adaptation of hypertension exercise prescription to the population.
详细描述
The 6-minute walking test (6MWT) has good universality and accessibility, and can be used as the basis for formulating exercise prescriptions. According to the consensus of Chinese experts on the application of clinical norms of the six-minute walking test, it is recommended to formulate individualized exercise prescriptions based on the average walking speed of 6MWT calculated from the six-minute walking distance (6MWD), but there is no relevant content about hypertension.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Overweight/obesity; Normal or normal high blood pressure after drug use; Grade 1 hypertension (whether taking medicine or not); Having sports habits; Sports risk is low and medium
排除标准
- •≥ grade 2 Hypertension; High-risk hypertensive patients; Malignant hypertension, secondary hypertension, etc; Serious arrhythmia, heart failure, acute myocardial infarction; Severe stroke, liver and kidney insufficiency; Physical dysfunction and failure to cooperate for various reasons; Unable to conduct CPET; The Types and doses of antihypertensive drugs is still in the process of adjustment
研究组 & 干预措施
CPET exercise prescription group
Formulate exercise prescription of cardiopulmonary exercise test (CPET) according to the principle of FITT [frequency, intensity, time and type]
干预措施: CPET exercise prescription (Behavioral)
6MWT exercise prescription group
Exercise prescription is set according to the recommendation of the Chinese expert consensus on the application of clinical norms of six-minute walking test
干预措施: 6MWT exercise prescription (Behavioral)
Regular exercise group
Carry out regular exercise as usual
干预措施: Regular exercise (Behavioral)
结局指标
主要结局
PWV
时间窗: through study completion, an average of 1 year
pulse wave velocity
weight
时间窗: through study completion, an average of 1 year
weight (kg)
Body mass index, BMI
时间窗: through study completion, an average of 1 year
body mass index （kg/m\^2）
Diastolic blood pressure, DBP
时间窗: through study completion, an average of 1 year
diastolic blood pressure (mmHg)
Heart rate, HR
时间窗: through study completion, an average of 1 year
Heart rate (beats/min)
Pulse wave velocity, PWV
时间窗: through study completion, an average of 1 year
pulse wave velocity
Systolic blood pressure, SBP
时间窗: through study completion, an average of 1 year
systolic blood pressure (mmHg)
次要结局
- circadian rhythm of blood pressure(through study completion, an average of 1 year)
- anxiety(through study completion, an average of 1 year)
- Blood lipids(through study completion, an average of 1 year)
- exercise hypertension(through study completion, an average of 1 year)
- use of antihypertensive drugs(through study completion, an average of 1 year)
- depression(through study completion, an average of 1 year)
研究者
Yang Xi
Doctor
Peking University People's Hospital