Load Quantitative MRI Study of Incipient LBP Patients.
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- the structure of lumbar
研究概览
简要总结
The mian purpose of this study is to analysis the imaging changes in 3.0T MRI of lumbar small joints, intervertebral discs, ligaments and muscle in hospital nurses first suffered with low back pain.
详细描述
Low back pain is a common clinical disease seriously affects the quality of people's lives. And this disease takes up a large proportion in the crowd. Incipient lumbago is hard to diagnose and often hidden morbidity. If early symptoms are ignored by patients, it will greatly influence the quality of life in the future. This study will use 3.0T MRI to distinguish the difference of lumbar small joints, intervertebral discs, ligaments and muscle between the normal and the pain.
Firstly, we recruit nurses with low back pain in one group, with the normal as control. Then the subject will accept 3.0T MRI scanning at the same time. Before scanning we will determine the MRI sequence to make sure the imageis are clear enough. At last, we will analysis the photos in the image processing workstation, reconstruct the anatomical structure in the scanning area. All of this is to find a possible reason or explanation in the occurrence of incipient lumbago through the comparison of two group's images.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 27 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female between 18 and 27 years of age
- •Subject who has worked as a nurse less than three years and will continue working as a nurse no less than one year
- •Back pain has happened more than 2 times In the past 12 months(every time lasts 2 days or more),or never happened
- •Subjects who do not participate any other study concerning pain prevention currently and in the next year
- •According with magnetic resonance inspection standard
- •NO spectical low back pain and no other serious diseases in the other systems
排除标准
- •Subjects who has a family history of low back pain
- •Subjects who are Suffering from specific low back pain
- •Subjects who are suffering from serious somatic disease and/or psychic disease
- •Subjects who are suffering from chronic pain disease and need long-term use of drug therapy
- •Subjects who are pregnant, planning to have a baby in 1 year or less than 6 months after delivery
- •Subjects who are suffering from chronic cardiac, respiratory, liver and kidney complaint symptomatically
- •Subjects who have had a spinal operation
结局指标
主要结局
the structure of lumbar
时间窗: 18 months
research the structure of facet joint,disc,muscle and ligment using quantitative MRI.
次要结局
- the function of lumbar(18 months)
研究者
Hongbin Lu
Professor
Central South University