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comparison of pain duration between dexmedtomidine and dexamathasone along with ropivacaine in ultrasound guided adductor canal block among patients undergoing unilateral total knee replacement

Phase 4
Conditions
Health Condition 1: I10- Essential (primary) hypertensionHealth Condition 2: E011- Iodine-deficiency related multinodular (endemic) goiterHealth Condition 3: E119- Type 2 diabetes mellitus without complications
Registration Number
CTRI/2024/01/061472
Lead Sponsor
believers church medical college hospita
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1)Patients posted for elective unilateral TKR under Subarachnoid block

2)ASA 1,11 grade of patients

3)Age group above 40 years

Exclusion Criteria

1) Patients refusal

2) Duration of surgery more than 2 hours

3)Patients with uncontrolled psychiatric illness

4)Patients with known allergy to local anaesthetics ,Morphine, Fentanyl or

Paracetamol.

5) Patients with peripheral neuropathy

6) Patients with known absolute contraindications to regional anaesthesi

Study & Design

Study Type
PMS
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1) To compare the duration of post-operative analgesia between Dexmedetomidine and Dexamethasone as adjuvants to 0.2% Ropivacaine in Adductor Canal Block among patients undergoing unilateral TKR . <br/ ><br> <br/ ><br>Timepoint: 24HOURS <br/ ><br> <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
Following postoperative Adductor Canal Block in Unilateral TKR. <br/ ><br>1) To compare postoperative pain at rest and during mobilisation of knee joint between the two groups. <br/ ><br>2) To compare the quality of sleep between the two groups. <br/ ><br>3) To compare the sedation sedation scores between the two groups. <br/ ><br>4) To compare the adverse effects like nausea, and vomiting, hemodynamic instability between two groups. <br/ ><br>Timepoint: 24HOURS
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