NL-OMON47323已完成不适用
To study the effect of LDL-cholesterol and LDL-cholesterol lowering on hematopoietic stem cells and circulating immune cells in familial hypercholesterolemia patients. - PRIME
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •- Age > 18 years old
- •- Familial hypercholesterolemia (according to Dutch Lipid network criteria)
- •- No previous cardiovascular events
- •- No current lipid lowering treatment
- •- LDL-cholesterol > 4.9 mmol/L;Healthy controls:
- •- Age >= 18 years old
- •- No (previous) clinically significant health problems
- •- No current medication use
排除标准
- •1. Malignant diseases or any clinically significant medical condition that could interfere with the conduct of the study in the opinion of the investigator.
- •2. Chronic or recent (<1 month) infections and/or clinical signs of acute infection and/or CRP>10
- •3. Auto-immune diseases
- •4. Recent or chronic immunosuppressant or antibiotic usage
- •5. Type I or II diabetes mellitus
- •6. Inability or unwillingness to comply with the protocol requirements, or deemed by investigator to be unfit for the study.
研究者
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