an exercise intervention study in NAFLD patients

E0 个研究点目标入组 15 人开始时间: 待定最近更新: 2024年2月28日

试验速览

暂无简介。

•Diagnosis of steatosis on transient elastography, conventional ultrasound, magnetic resonance imaging, computed tomography, liver biopsy, or identified as steatotic subject by fatty liver index (FLI) algorithm which is based on waist circumference, body mass index, and levels of triglyceride and ?-glutamyltransferase
•-18-70 years of age
•-BMI < 40 kg/m2

•-Acute illness or current evidence of acute or chronic inflammatory or infective diseases
•-Abusive alcohol use (> 20 IU/week for men, > 14 IU/week for women)
•-Diagnosed liver cirrhosis and/or hepatocellular carcinoma
•-Diagnosed cardiorespiratory, neurological or musculoskeletal disease
•-Diagnosed insulin or GLP-1 agonist treated type 2 diabetes or type 1 diabetes
•-Hepatitis B and/or C or auto-immune hepatitis
•-Wilsons disease/alpha-1-antitripsine deficiency
•-Hemochromatosis
•-Hypothyroidism
•-Lipoatrophy
•-Bleeding disorder or anti-coagulant use which cannot be temporarily discontinued
•-Not able or willing to undergo MRI (for example claustrophobia, ICD, pacemaker)
•-Diagnosed depression or any mental illness rendering the patients unable to understand the nature, scope and possible sequences of the study
•-Any participation in regular exercise and/or diet program more than 2 times per week in the 3 months prior to recruitment

发起方