Efficacy of cryo-vibro-analgesia on propofol injection pain in paediatric patients undergoing surgery under general anaesthesia: A randomised control study

Propofol is the most common intravenous anesthetic drug used for induction and maintenance of general anesthesia owing to its rapid onset, short duration and favourable safety profile. However, the incidence of pain following propofol injection is seen in approximately 70% patients. The methods of pain relief during propofol injection include pharmacological and non-pharmacological means. The most accepted technique is administration of lignocaine either mixed in the syringe or administered prior to injection of propofol. This study aims to evaluate effect of cryo-vibro-analgesia technique using Buzzy device on pain associated with propofol injection in children (5-12years) undergoing surgery under general anaesthesia. Though multiple studies have evidenced the role of Buzzy device and its cryo-vibro-analgesia on mitigation of pain in vaccinations and insertion of IV cannula, there is no study on its effectiveness in reducing propofol injection pain in children. In this study after taking written informed consent, patients will be randomized into either treatment or control group. In treatment group Buzzy device will be fixed 5cm above the cannulation site along with frozen wings and turned on for 1min before propofol injection. In control group Buzzy device will be applied similarly with unfrozen wings and not switched on. During the propofol injection, pain will be assessed and graded using a composite behavioral scale. Following induction the study will be terminated and monitoring will continue for 24 hours.