To Compare Efficacy Of The Injection Propofol Vs Injection Etomidate During General Anaesthesia In Adult
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- To Check The Effect Of Injection Propofol And Injection Etomidate
研究概览
简要总结
Induction of anaesthesia is a crucial period during anaesthesia delivery, often associated with significant hemodynamic fluctuations. Hypotension and arrhythmias during induction can affect patient outcomes, especially those with co-morbid conditions.
Propofol is a frequently used induction agent due to its rapid onset and smooth induction; however, it is well documented to cause marked reduction in arterial pressure and peripheral resistance. Etomidate, on the other Hand Is non barbiturate hypnotic agent which provides a more stable hemodynamic profile during induction, making it desirable in patients with poor cardiovascular reserve.
This study aims to directly compare the effects of Propofol and Etomidate on hemodynamics during induction of anaesthesia in a population of ASA I and II adults undergoing elective surgeries under general anaesthesia.
The results of this study may help guide anaesthesiologist in choosing the most appropriate induction agent in their practice, particularly for patients at risk of hemodynamic instability.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •ASA Grade 1 and 2 Elective surgeries under general anaesthesia.
排除标准
- •Hypersensitivity to drug Pregnancy and lactation Patient refusal for participation in study.
结局指标
主要结局
To Check The Effect Of Injection Propofol And Injection Etomidate
时间窗: From Starting Of Induction,Intra-op And Post-op Up To 10 Minutes
次要结局
未报告次要终点
研究者
DR RAGHU DHIRUBHAI SURANI
Gujrat adani institute of medical science
