To Compare Efficacy Of The Injection Propofol Vs Injection Etomidate During General Anaesthesia In Adult
Overview
- Phase
- Phase 4
- Status
- Not yet recruiting
- Sponsor
- Gujarat Adani Institute of Medical Science
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- To Check The Effect Of Injection Propofol And Injection Etomidate
Overview
Brief Summary
Induction of anaesthesia is a crucial period during anaesthesia delivery, often associated with significant hemodynamic fluctuations. Hypotension and arrhythmias during induction can affect patient outcomes, especially those with co-morbid conditions.
Propofol is a frequently used induction agent due to its rapid onset and smooth induction; however, it is well documented to cause marked reduction in arterial pressure and peripheral resistance. Etomidate, on the other Hand Is non barbiturate hypnotic agent which provides a more stable hemodynamic profile during induction, making it desirable in patients with poor cardiovascular reserve.
This study aims to directly compare the effects of Propofol and Etomidate on hemodynamics during induction of anaesthesia in a population of ASA I and II adults undergoing elective surgeries under general anaesthesia.
The results of this study may help guide anaesthesiologist in choosing the most appropriate induction agent in their practice, particularly for patients at risk of hemodynamic instability.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •ASA Grade 1 and 2 Elective surgeries under general anaesthesia.
Exclusion Criteria
- •Hypersensitivity to drug Pregnancy and lactation Patient refusal for participation in study.
Outcomes
Primary Outcomes
To Check The Effect Of Injection Propofol And Injection Etomidate
Time Frame: From Starting Of Induction,Intra-op And Post-op Up To 10 Minutes
Secondary Outcomes
No secondary outcomes reported
Investigators
DR RAGHU DHIRUBHAI SURANI
Gujrat adani institute of medical science