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临床试验/CTRI/2025/11/097089
CTRI/2025/11/097089尚未招募4 期

To Compare Efficacy Of The Injection Propofol Vs Injection Etomidate During General Anaesthesia In Adult

Gujarat Adani Institute of Medical Science1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2025年11月10日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
150
试验地点
1
主要终点
To Check The Effect Of Injection Propofol And Injection Etomidate

研究概览

简要总结

Induction of anaesthesia is a crucial period during anaesthesia delivery, often associated with significant hemodynamic fluctuations. Hypotension and arrhythmias during induction can affect patient outcomes, especially those with co-morbid conditions.

Propofol is a frequently used induction agent due to its rapid onset and smooth induction; however, it is well documented to cause marked reduction in arterial pressure and peripheral resistance. Etomidate, on the other Hand  Is non barbiturate hypnotic agent which provides a more stable hemodynamic profile during induction, making it desirable in patients with poor cardiovascular reserve.

This study aims to directly compare the effects of Propofol and Etomidate on hemodynamics during induction of anaesthesia in a population of ASA I and II adults undergoing elective surgeries under general anaesthesia.

The results of this study may help guide anaesthesiologist in choosing the most appropriate induction agent in their practice, particularly for patients at risk of hemodynamic instability.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • ASA Grade 1 and 2 Elective surgeries under general anaesthesia.

排除标准

  • Hypersensitivity to drug Pregnancy and lactation Patient refusal for participation in study.

结局指标

主要结局

To Check The Effect Of Injection Propofol And Injection Etomidate

时间窗: From Starting Of Induction,Intra-op And Post-op Up To 10 Minutes

次要结局

未报告次要终点

研究者

发起方
Gujarat Adani Institute of Medical Science
申办方类型
Other [Self funded]
责任方
Principal Investigator
主要研究者

DR RAGHU DHIRUBHAI SURANI

Gujrat adani institute of medical science

研究点 (1)

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