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Effectiveness of concentrated growth factor and laser on inferior alveolar nerve injury and periodontal bone defect after mandibular impacted wisdom tooth extractio

Phase 2
Completed
Conditions
inferior alveolar nerve injury and periodontal bone defect after mandibular impacted wisdom tooth extraction
Mandibular Impacted Wisdom Teeth, Inferior alveolar nerve injury, Distal Bone Defects , Concentrated Growth Factor, Lasers, Periodontal probe depth
Registration Number
TCTR20230704001
Lead Sponsor
Foshan Stomatological Hospital
Brief Summary

Both CGF and laser could significantly accelerate the recovery of IAN injury after mandibular impacted wisdom tooth extraction, but there was no significant difference in the efficacy of CGF and laser in promoting IAN recovery

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
31
Inclusion Criteria

1) patients were diagnosed with IAN injury after the Extraction of impacted mandibular wisdom teeth; 2) cbct or panoramic photograph showed that there was no significant teeth decay, alveolar bone resorption, or other jaw lesions in the distal part of the adjacent second molar; 3) the impacted wisdom teeth had no pericoronitis and no significant shadow at the root tip; 4) aged 18 years or over.

Exclusion Criteria

1) complicated with severe cardiovascular diseases or blood system diseases; 2) having a periodontal disease in the distal part of the adjacent second molar before the operation; 3) taking drugs affecting bone or soft tissue healing before; 4) osteoporosis; 5) poor oral hygiene; and 6) smoking and drinking.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
recovery of injured nerves 1 and 3 month after operation VAS and PP tests
Secondary Outcome Measures
NameTimeMethod
regeneration of periodontal bone defect 1 and 3 month after operation periodontal probing depth
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