Exploratory study of rehabilitation during hemodialysis and nutrition therapy for hemodialysis patients with sarcopenia

Not Applicable

• Conditions: End-stage Kidney Disease (on Hemodialysis)

• Registration Number: JPRN-UMIN000039104
• Lead Sponsor: Sapporo Medical University, School of Medicine

Brief Summary

At baseline, 4 of 16 hemodialysis patients (age 71.5 [Q1 64.8, Q3 78.0] years, 50% female) had sarcopenia based on AWGS criteria. Consent was obtained for 3 of the 16 patients, and the "dialysis rehabilitation (nutritional therapy + exercise therapy)" indicated in this study was implemented. No improvement in sarcopenia, the primary endpoint, was obtained, but this was thought to be largely a matter of sample size.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-01-10
• Study Completion: 2021-09-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 3

Inclusion Criteria

Not provided

Exclusion Criteria

Excludes limb deficiency, history of orthopedic surgery within 3 months, age under 18, age 90 and older, history of malignant disease, history of spinocerebellar degeneration, and pregnant women

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sarcopenia improvement in study subjects after 6 months

Secondary Outcome Measures

Name	Time	Method
Changes in various blood data, body components (lower limb muscle mass, upper limb muscle mass, skeletal muscle index), MIS (Malnutrition Inflammation Score), GNRI (Geriatric Nutritional Risk Index), QIDS-J (Quick Inventry of Depressive Symptomatology)