Variation of Progesterone in IVF Cycles
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The variation of serum progesterone around the ovulation triggering in IVF-cycles
研究概览
简要总结
to examine if a natural daytime variation in progesterone levels may explain parts of the inconsistent findings from studies reporting divergent results concerning this matter and will be carried out by several blood samples from the same patient during the day of ovulation triggering.
详细描述
The impact of the progesterone level at the end of the follicular phase in stimulated IVF/ICSI cycles and its effect on the pregnancy rate and oocyte quality is controversial, which arises from conflicting results in retrospective studies and meta-analyses. This study is assumed to examine if a natural daytime variation in progesterone levels may explain parts of the inconsistent findings from studies reporting divergent results concerning this matter and will be carried out by several blood samples from the same patient during the day of ovulation triggering. If variation is present, the impact of variation on the developing oocyte and embryo quality will be estimated by embryo quality indicators.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •patients 18-45 years
- •BMI 18-35 kg/m2
- •Menstrual cycle length 24-35 days
- •Stimulation with rFSH or hMG
排除标准
- 未提供
结局指标
主要结局
The variation of serum progesterone around the ovulation triggering in IVF-cycles
时间窗: 6-8 months
the circadian secretion-pattern of progesterone during early follicular phase of normal cycling females
次要结局
未报告次要终点