Effectiveness of Toothpaste Containing the Active Ingredient of Galla Chinensis Extract on Treating Dentin Hypersensitivity '' A Randomized Clinical Trial ''

Minia University1 site in 1 country90 target enrollmentMay 20, 2021

ConditionsTooth Sensitivity

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Tooth Sensitivity
Sponsor: Minia University
Enrollment: 90
Locations: 1
Primary Endpoint: Change of pain level in response to stimuli
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This clinical trial was conducted to compare the desensitizing effect of toothpaste containing the active ingredient of an extract of Galla chinensis and toothpaste containing fluoride in patients with dentin hypersensitivity.

Registry

clinicaltrials.gov

Start Date

May 20, 2021

End Date

June 25, 2022

Last Updated

2 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Minia University

Responsible Party

Principal Investigator

Ibram ibrahim morkous henein

principal investigator

Minia University

Eligibility Criteria

Inclusion Criteria

•Age \>18 years.
•Overall good oral hygiene status.
•Participants show tooth neck abrasion or gingival retraction.
•Patients have subjective dentin hypersensitivity (at least 1 tooth) after using airflow.
•No history of periodontal treatment, including periodontal surgery, in the past year.
•Written informed consent

Exclusion Criteria

•Patient with severe periodontitis or severe erosion damage.
•Patients with a compromised medical history, or had received therapeutic irradiation to the head and neck region.
•Medically compromised patients where pain levels would be compromised.
•If analgesics or antibiotics have been administrated by the patient during the past 12 hours preoperatively as it might alter their pain perception.
•Patients reporting bruxism or clenching in order to avoid further pressure on an already hypersensitive tooth inducing subsequent irritation and inflammation.
•Teeth that show association with acute periapical abscess and swelling.
•Greater than grade I mobility or pocket depth greater than 5mm.
•Non-restorable teeth or hopeless teeth.
•Immature teeth.
•Radiographic evidence of external or internal root resorption.

Outcomes

Primary Outcomes

Change of pain level in response to stimuli

Time Frame: 6 months follow up

Teeth were evaluated at baseline (T0), 1week (T1), 2 weeks (T2), 4 weeks (T3), 3 months (T4), and 6 months (T5) after using different types of toothpastes using Visual Analog Scale (VAS) scoring from 0-10 while 0 mean no pain and 10 severe pain by sensitivity tests (schiff test )