Comparative Evaluation of Intra-operative Peritoneal Lavage With Super Oxidized Solution and Normal Saline in Peritonitis Cases
- Conditions
- Peritonitis
- Interventions
- Procedure: Super Oxidized Solution in group I
- Registration Number
- NCT02882932
- Lead Sponsor
- Maharishi Markendeswar University (Deemed to be University)
- Brief Summary
Super Oxidized Solution (SOS) was used in peritonitis and results were compared by using normal saline solution in two groups. Abdominal fluid was taken to check for bacterial load after giving lavage with SOS solution and in other group normal saline. SOS is a high level disinfectant, non-flammable and no special training is required to handle it.
- Detailed Description
Aim - To investigate the efficacy of super-oxidized solution (SOS) over normal saline in peritonitis. The investigators objectives are to present the potential clinical impact of intraperitoneal lavage with solutions for early recovery of the patient by reducing the infection rate.
Methods - A double-blind random clinical trial was performed in 240 patients diagnosed as peritonitis at MMIMSR, Mullana, Ambala, India, from December 2014 - November 2015. Subjects were divided into 2 groups, i.e. 120 patients in the study group and 120 cases in the control group. Both the groups underwent peritoneal lavage ; the study group received SOS where as control group underwent normal saline lavage. The effectiveness of both the solutions were compared.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 290
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Super Oxidized Solution Super Oxidized Solution in group I Procedure/Surgery: Super Oxidized Solution(SOS) in group I - SOS with normal saline solution was used normal saline Super Oxidized Solution in group I Procedure/Surgery: normal saline In group II - patients underwent normal saline wash and bacterial load was noted.
- Primary Outcome Measures
Name Time Method the investigators measured the infection rate by checking the bacterial load during after surgery average of one year The investigators asked about the infection, early recovery
- Secondary Outcome Measures
Name Time Method The Results Were Measured In the Form of the, Early Recovery, Early Bowel Sounds With in 10 -20 days the condition of the patient measured in the form of early bowel sounds, fever and discharge from the operated area