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Clinical Trials/NCT04463498
NCT04463498
Recruiting
Not Applicable

Sleep in Psychiatric Care: A Transdiagnostic Group-based Sleep-school as Treatment for Comorbid Insomnia

Haukeland University Hospital1 site in 1 country60 target enrollmentDecember 17, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sleep Disorder; Insomnia Type
Sponsor
Haukeland University Hospital
Enrollment
60
Locations
1
Primary Endpoint
Insomnia symptoms
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

Sleep disorders commonly co-occur with psychiatric disorders. Sleep disorders are often treated with medication or not at all in psychiatric care, although there exist a plethora of documentation of the effectiveness of sleep interventions. There is also an increase in studies showing effectiveness of sleep-interventions when the sleep disorder co-occurs with psychiatric illness. The most common and best documented treatment for insomnia is cognitive behavioral therapy for insomnia (CBTi). There is a great gap in the knowledge on how sleep disorders can be treated effectively in psychiatric care. In this project the investigators therefore seek to investigate the effect of non-pharmacological, group-based treatment in a randomized controlled trial (RCT) where sleep and psychiatric symptoms are the primary outcome measures. CBTi comprise of sleep education, sleep restriction, stimulus control and cognitive restructuring of dysfunctional thoughts about sleep.

Detailed Description

The recommended treatment for insomnia is CBTi. Recent research has proven that dark therapy, or blocking light in wavelengths \<530 nm by the use of for example orange blue-blocking glasses (bb-glasses), has shown the ability to maintain melatonin production comparable to darkness and to have an additive effect in the treatment of insomnia. The investigators therefore also want to test bb-glasses as an additive treatment to CBTi for insomnia. The sleep-school at Bjørgvin District Psychiatric Hospital (DPS) is an already established treatment since 2017. The insomnia-group gets together every other Monday from noon until 2 pm. The group is open, which means that participants start at different dates and meet people in the group that might be at the end of their CBTi treatment. Participants are patients at the general psychiatric outpatient clinic at Bjørgvin DPS. Participant have been referred to the sleep-team by their psychologist or doctor. In this RCT the investigators will carry on the same structure for the group for participants that are recruited to the RCT. All participants have an individual consultation before joining the group where the focus is on eligibility to participate in the group-based treatment, diagnostic evaluation, receive a standardized education on sleep-regulation and sleep hygiene advice and receive a date to start the group-based CBTi treatment. In a randomized manner, they will be allocated to the sleep-school group and start the treatment on the next possible date or to a 8 week wait-list and receive a date the treatment starts. All eligible participants will be informed that there may be a waitlist and receive a start-date without being informed that thay are in a waitlist group or not a waitlist group. All participants will be treated as usual (TAU) for their psychiatric problems parallel to either sleep-school or waitlist. Participants that start sleep-school as soon as possible, are also allocated to a) ordinary group-based CBTi 8 weeks or b) group-based CBTi 8 weeks and bb-glasses. All participant will be followed up after 12 months.

Registry
clinicaltrials.gov
Start Date
December 17, 2021
End Date
December 31, 2027
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Haukeland University Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients referred to the sleep-school at Bjørgvin DPS psychiatric hospital
  • Patients fulfilling the Diagnostic Manual for Mental Disorders (DSM-V) criteria for insomnia comorbid to moderate to severe psychiatric illness (confirmed F-diagnosis based on the International Statistical Classification of Diseases and Related Health Problems (ICD-11) diagnostic system that are used in Norway in addition to insomnia and/or scores of ≥19 on BDI and/or scores of ≥16 on BAI at the time of referral to the sleep school)

Exclusion Criteria

  • Nightwork
  • Patients that do not fulfil the DSM-V criteria for insomnia comorbid to moderate to severe psychiatric illness (confirmed F-diagnosis based on the ICD-10 diagnostic system that are used in Norway in addition to insomnia and/or scores of ≥19 on BDI and/or scores of ≥16 on BAI at the time of referral to the sleep school)

Outcomes

Primary Outcomes

Insomnia symptoms

Time Frame: baseline, bi-weekly and post intervention after 8 weeks, follow-up after 12 months

Measured by the questionnaires Insomnia severity Index (ISI) and Bergen Insomnia Scale (BIS). From sleep diaries; sleep onset latency (SOL), wake after sleep onset (WASO) and sleep efficiency (SE).

Secondary Outcomes

  • Changes in objective wake after sleep onset (WASO)(baseline and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in Daytime function (DF)(baseline, bi-weekly assesment and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in objective sleep onset latency (SOL)(baseline and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in fatigue(baseline and post intervention after 8 weeks, and at follow-up after 12 months)
  • Changes in insomnia severity(baseline and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in objective total sleep length/time asleep (TST),(baseline and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in Total sleep length/time asleep (TST)(baseline, bi-weekly assesment and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in Sleep quality (SQ)(baseline, bi-weekly assesment and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in beliefs and attitudes about sleep(baseline and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in Time in bed (TIB)(baseline, bi-weekly assesment and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in objective early morning awakening (EMA)(baseline and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in anxiety(baseline and post intervention after 8 weeks, follow-up after 12 months)
  • Work status(baseline and post intervention after 8 weeks, and at follow-up after 12 months)
  • Changes in insomnia diagnosis(baseline and post intervention after 8 weeks, follow-up after 12 months)
  • Well-being(baseline and post intervention after 8 weeks, and at follow-up after 12 months)
  • Changes in Early morning awakening (EMA)(baseline, bi-weekly assesment and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in objective time in bed (TIB)(baseline and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in objective sleep efficiency (SE)(baseline and post intervention after 8 weeks, follow-up after 12 months)
  • Changes in depression(baseline and post intervention after 8 weeks, follow-up after 12 months)

Study Sites (1)

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