Comparison of Post-Operative Analgesia With Peri Tract Local Anesthesia Infiltration and Oral Analgesia Versus Post-Operative Intravenous Analgesia After Percutaneous Nephrolithotomy.
Overview
- Phase
- Phase 4
- Intervention
- Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg.
- Conditions
- Pain
- Sponsor
- Armed Forces Institute of Urology, Rawalpindi
- Enrollment
- 68
- Locations
- 1
- Primary Endpoint
- Comparison of Post-Operative Analgesia With Peri Tract Local Anesthesia Infiltration and Oral Analgesia Versus Post-Operative Intravenous Analgesia After Percutaneous Nephrolithotomy.
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The rationale of this study was to compare the efficacy of peri-tract bupivacaine infiltration with intravenous post-operative analgesia following PCNL in reference to the context with the previous studies so that we can adopt the better technique to curtail the post-operative pain.
Detailed Description
The rationale of this study was to compare the efficacy of peri-tract bupivacaine infiltration with intravenous postoperative analgesia following PCNL in reference to the context with the previous studies so that we can adopt the better technique to curtail the post-operative pain.
Investigators
Musab Umair Khalid
Doctor
Armed Forces Institute of Urology, Rawalpindi
Eligibility Criteria
Inclusion Criteria
- •all patients undergoing PCNL
- •age from 12-65 years
- •normal renal functions
- •no history of chronic pain
- •ASA I, II \& III
- •Both genders
Exclusion Criteria
- •history of local anaesthesia allergy
- •Redo PCNL
- •Multiple punctures during PCNL
- •Excessive intra-operative bleeding
- •Diabetes mellitus
- •Coagulopathy
- •Mental disorder
- •ASA IV \& V
- •Active urinary tract infection.
Arms & Interventions
Local Anesthesia
Group A patients received peri tract local anaesthesia infiltration with 0.25% Bupivacaine.
Intervention: Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg.
Local Anesthesia
Group A patients received peri tract local anaesthesia infiltration with 0.25% Bupivacaine.
Intervention: paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.
Intravenous Analgesics
Group B patients received postoperative intravenous analgesia.
Intervention: Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg.
Intravenous Analgesics
Group B patients received postoperative intravenous analgesia.
Intervention: paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.
Outcomes
Primary Outcomes
Comparison of Post-Operative Analgesia With Peri Tract Local Anesthesia Infiltration and Oral Analgesia Versus Post-Operative Intravenous Analgesia After Percutaneous Nephrolithotomy.
Time Frame: 6 months
Efficacy of peri-tract infiltration of bupivacaine over standard oral analgesia in patients undergoing PCNL. Measurement: Postoperative pain Measurement tool: Visual analog scale