A Comparison of Postoperative Outcomes Provided by a Continuous Preperitoneal Infusion Versus Ultrasound Guided Transversus Abdominis Plane Block for Abdominoplasty
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 主要终点
- self reported pain intensity in the morning ,afternoon,evening, during activity over the past 2 days
研究概览
简要总结
aim of this study is to compare the postoperative analgesia provided bya continuous preperitoneal infusion versus ultrasound guided rectus sheath block for midline emergency laparotomy.
anticoagulated patients
详细描述
Patients and Methods:
This randomized prospective study will be carried out after the approval of Rashid Hospital's Research Ethical Committee and patient's written informed consent.
Sixty adult patients , of both gender , 18-70 years old, ASA I-III who will be scheduled for emergency laparotomy with upper abdominal midline incision will be included in the study. Exclusion criteria will be patients with known allergic response or contraindications to paracetamol, parecoxib, morphine or ropivacaine and pregnant women
The enrolled patients will be randomly assigned to one of three groups:
Group I ( 20 patients) will receive an ultrasound guided rectus sheath block by the end of the surgery using 15 ml ropivacaine 0.5% on either side.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA-1 to ASA-3,emergency midline laparotomy
排除标准
- •ASA-4 & above,allergic patients to the study's medications ,morbid obeses patients,patient refusal,age below 18yrs
研究组 & 干预措施
Group I
( 20 patients) will receive an ultrasound guided rectus sheath block by the end of the surgery using 15 ml ropivacaine 0.5% on either side.
干预措施: an ultrasound guided rectus sheath block (Procedure)
Group II
( 20 patients) multiholed catheter will be inserted at the end of surgery and after the closure of the peritoneal layer, a10 ml bolus of ropivacaine 0.2% will be administered through the catheter and then connected to an elastomeric pump delivering a continuous fixed -rate of ropivacaine 5ml/h.
干预措施: multiholed catheter (Procedure)
Group III
( 20 patients) a multiholed catheter will be inserted as in Group II and will receive also an ultrasound guided rectus sheath block as described for Group I.
干预措施: an ultrasound guided rectus sheath block &multiholed catheter (Procedure)
结局指标
主要结局
self reported pain intensity in the morning ,afternoon,evening, during activity over the past 2 days
时间窗: 2 days
each item is scored (0-10)0=no pain\& 10= the worst
次要结局
未报告次要终点
研究者
Dr Manar Mamdouh Fahmy Elsharkawi
anaesthesiologist
Dubai Health Authority