Investigation of the effect of intravenous vitamin C on definite patients with coronavirus pneumonia

Phase 2

Conditions: COVID 19 PNEUMONIA.
U07.1
This code assigned to a disease diagnosis of COVID-19 confirmed by laboratory testing.

Registration Number: IRCT20200516047468N1

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 50

Inclusion Criteria

Patients who have a positive corona pcr test.
Patients over 18 years of age.
Oxygen saturation should be below 93%.
The patient's respiratory rate should be more than 30 per minute.
Lung involvement in chest or CT scans of the lungs is more than 50 percent.

Exclusion Criteria

Allergy to vitamin C
The patient's shortness of breath may be due to cardiac pulmonary edema
Be pregnant or breastfeeding
Have chronic kidney disease
Be in diabetic ketoacidosis
Have kidney stones

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The amount of lung involvement in a CT scan: According to the radiologist, the appearance of lung involvement and the percentage of lung involvement are measured. Timepoint: Five days after receiving vitamin C intravenously. Method of measurement: According to the radiologist, the appearance of lung involvement and the extent of lung involvement are scoring.

Secondary Outcome Measures

Name	Time	Method
Oxygen saturation rate of patients. Timepoint: Five days after receiving vitamin C intravenously. Method of measurement: Using an pulse oxymeter.;Respiratory rate of patients. Timepoint: Five days after receiving vitamin C intravenously. Method of measurement: Examination by a doctor.;Serum CRP level. Timepoint: Five days after receiving vitamin C intravenously. Method of measurement: Report by Laboratory.;Lymphopenia rate. Timepoint: Five days after receiving vitamin C intravenously. Method of measurement: Report by Laboratory.;Mortality rate. Timepoint: At the end of the patient's hospitalization. Method of measurement: report by doctor.;Duration of hospitalization. Timepoint: At the end of the patient's hospitalization. Method of measurement: Calculated by a physician.;Intubation rate. Timepoint: At the end of the study. Method of measurement: Calculated by the analyzer.