Pre-surgical Antisepsis of Hands After Washing With Triclosan 0.5% Compared to Propan-1-ol 60%

Phase 4

Completed

• Conditions: Antisepsis
• Interventions: Drug: propanolol; Drug: Triclosan 0.5 % Topical Solution

• Registration Number: NCT04538365
• Lead Sponsor: Centro Ortopedico y Quirurgico del Pie

Brief Summary

The present study evaluates the effects of bactericidal load reduction after surgical hand scrub antisepsis using the reference antiseptic product propanol-

1 60% as control versus a surgical hand scrub antisepsis with triclosan 0.5% in order to test if pass the standard european norm 12791.

Detailed Description

The investigators conducted a crossover clinical trial to evaluate the antiseptic effectiveness of preoperative surgical scrubbing using propan-ol-1 60% by scrub using the reference antiseptic product propan-ol-1 60% as control versus a surgical hand scrub antisepsis with trocilosan 0.5% in order to test if pass the standard european norm 12791. Samples will be taken from the hands of each volunteer after a surgical hands antiseptic.

Study Timeline

• Study First Submitted: 2020-08-29
• Study First Submitted QC: 2020-08-29
• Study First Posted: 2020-09-04
• Status Verified: 2020-10
• Study Start: 2020-10-01
• Primary Completion: 2020-10-20
• Study Completion: 2020-10-30
• Last Update Submitted: 2020-10-30
• Last Update Posted: 2020-11-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Participants without systemic pathologies, with healthy skin of the hands and short fingernails.
• They do not use substances with antibacterial action.

Exclusion Criteria

• Taken antibiotics before 10 days of the intervention.
• Wear any jewellery on the hands

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Hand antisepsis with propanolol-1 60%	propanolol	Effectiveness of pre-surgical hand washing in reducing bacterial load using propanolol-1 60% as control
Hand antisepsis with triclosan solution	Triclosan 0.5 % Topical Solution	Effectiveness of pre-surgical hand washing in reducing bacterial load using triclosan 0.5% solution

Primary Outcome Measures

Name	Time	Method
Reduction of bacterial load immediately after hand scrub	Change from bacterial load at 5 minutes	Participants will scrub with the antiseptic solution vigorously from hand to the wrists according with the standard handscrub procedure

Secondary Outcome Measures

Name	Time	Method
Reduction of bacterial load after 3 hours of hand scrub	Change from bacterial load after 3 hours	Participants will scrub with the antiseptic solution vigorously from hand to the wrists according with the standard handscrub after 3 hours

Trial Locations

Locations (1)

Facultad de Enfermeria, Fisioterapia y Podologia; 🇪🇸 Madrid, Spain