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Screening and intervention for subclinical coronary artery disease in patients with type 2 diabetes: THE STENO INTEN-CT STUDY

Phase 1
Recruiting
Conditions
Type 2 diabetes
MedDRA version: 21.1Level: PTClassification code: 10067585Term: Type 2 diabetes mellitus Class: 100000004861
Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Registration Number
CTIS2022-500143-21-01
Lead Sponsor
Aarhus University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
7300
Inclusion Criteria

New or former diagnosis of T2DM according to WHO., Age between 55-69 years (men) and 60-74 years (women)., Signed declaration of consent

Exclusion Criteria

Previous history of CVD (previous myocardial infarction or coronary intervention (percutaneous coronary intervention or by-pass), heart failure, stroke or peripheral artery disease as documented by the patient or the patient medical record)., Contraindications or allergies to both SGLT2 inhibitors and GLP-1 analogues., Signs of critical cardiac disease: >50% stenosis of left main coronary artery (CT angiography) or left ventricular ejection fraction below 30% (echocardiography). If a CT angiography is not available, a CAC>1000 on the non-contrast cardiac CT will be considered equal to critical cardiac disease., Expected life duration < 1 year for any reason.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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