MedPath

Replacement of invasive diagnostic coronary procedures by innovative noninvasive Imaging Technologies

Recruiting
Conditions
Atherosclerosis
Coronary artery disease
10011082
Registration Number
NL-OMON47060
Lead Sponsor
niversitair Medisch Centrum Groningen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
440
Inclusion Criteria

- Planned for a ICA as part of standard clinical care for evaluation of suspected CAD
- Age >=18 years

Exclusion Criteria

- Unable to provide written informed consent
- ICA planned for other reasons than suspected obstructive CAD (e.g. screening prior to lung transplantation, valvular surgery, or ICD implantation)
- Significant arrhythmia deemed to interfer with successful ECG triggered non-invasive imaging as judged by a cardiologist.
- Renal insufficiency: GFR <50ml/min
- Known anaphylactic allergy to iodine
- Known severe comorbidities with a life expectancy of less than 1 year
- Known severe claustrophobia
- Known contra-indications for beta-blocker or adenosine
- Instable coronary artery disease (acute coronary syndrome or instable angina)
- Other contraindications for CTA or MR perfusion (e.g. presence of incompatible pacemaker or ICD devices/leads, pregnancy, BMI >35 kg/m2).

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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