Percutaneous coronary intervention for chronic total occlusion in octogenarians - a propensity score study

• Conditions: I25.1; Atherosclerotic heart disease

• Registration Number: DRKS00025882
• Lead Sponsor: Zentrum für Kardiologie Universitätsmedizin Mainz

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-07-30
• Study Completion: 2021-09-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 258

Inclusion Criteria

All patients who underwent CTO PCI at the Universitätemedizin Mainz. Consenting patients over 18 years of age

Exclusion Criteria

Patients under 18 years of age
Patients who are not capable of giving consent

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint of the retrospective analysis of our patient cohort study was defined as follows:<br>(1) Re-occlusion: Defined as TIMI flow grade 0, as assessed by fluoroscopy of the treated vessel at the timepoint of surveillance coronary angiography<br>(2) Target vessel failure (TVF): Defined as a combined endpoint by the presence of re-occlusion, restenosis, or target vessel revascularization (defined as a necessity for a repeated PCI within the former CTO vessel)

Secondary Outcome Measures

Name	Time	Method
Secondary outcome bleeding, vascular access complications requiring medical treatment and acute kidney injury (AKI). Bleeding was defined in accordance to the Academic Research Consortium. Type 3-5 bleedings were recorded. Acute kidney injury (AKI) was defined as an abrupt decrease in kidney function, according to the KDIGO AKI Guideline Work Group)