The Effect of Various dosage of Ketamin on postoperative pain in opiate-dependent patients undergoing orthopedic surgery
Early Phase 1
- Conditions
- pper and lower limb fractures.
- Registration Number
- IRCT20230804059031N1
- Lead Sponsor
- Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Patients with a history of drug abuse
18-65 years
Exclusion Criteria
Patients with multiple trauma
Consumption of alcohol and artificial drugs not derived from opium
Patients should have continuous use of drugs other than narcotics
Lack of patient consent for the study
Non-cooperation of the patient after entering the study
History of seizures or drug sensitivity to ketamine and other contraindications to ketamine
History of cardiovascular diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Investigating the effectiveness of different doses of ketamine on postoperative pain in drug addicts undergoing orthopedic surgery for fractures of the distal radius, femur and tibia. Timepoint: 2, 6, 12 and 25 hours after the operation. Method of measurement: 1 to 10.
- Secondary Outcome Measures
Name Time Method