Effect of ketamine (study drug) on delirium after surgery
Not Applicable
- Conditions
- Health Condition 1: F05- Delirium due to known physiological condition
- Registration Number
- CTRI/2023/06/054111
- Lead Sponsor
- Sir Ganga Ram Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age>=65years
ASA physical status I-III
Both males & females
Informed Consent
Exclusion Criteria
Patients previously diagnosed with dementia or stroke severe psychiatric or neurological diseases
Patients with known uncompensated cardiovascular disease or hepato-renal insufficiency or uncontrolled endocrine disease
Patients on an anti-depressant or anti-anxiety or anti-convulsant and anti-parkinsonism drugs
Known case of severe visual or auditory dysfunction
Known alcohol or substance abuse
Preoperative cognitive impairment as assessed by 4A test >=4 is delirium
Inability to perform neurocognitive tests
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative Delirium <br/ ><br>4A Test â?¥ 4Timepoint: 1hr, 6hr after surgery and every day morning till discharge or postoperative day 7
- Secondary Outcome Measures
Name Time Method Hallucinations <br/ ><br> <br/ ><br>Timepoint: first 24 hrs. <br/ ><br> <br/ ><br>;Intraoperative hemodynamic instabilityTimepoint: Intraoperatively;Postoperative nausea and vomiting as assessed by a 3-point Likert scale.Timepoint: During first 24 hrs;Postoperative pain assessed by numerical rating scale.Timepoint: During first 24hrs