Effects of Resistance Training Performed in the Fasted State Compared to the Fed State on Morphological and Neuromuscular Adaptations in Young Adults
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Fasting
- Sponsor
- Federal University of Rio Grande do Sul
- Enrollment
- 28
- Locations
- 1
- Primary Endpoint
- Lean body mass
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
It is well evidenced in the literature that fasting aerobic exercise generates a series of metabolic differences when compared to exercise performed in the fed state, including the use of fats predominantly as an energy source. Consequently, increases in adaptations to aerobic training, related to health and physical performance, are observed when sessions are performed in the fasted state. In relation to resistance training, the evidence is limited. There is a lack of data in the literature regarding the effects of fasting on resistance exercises and whether this practice may reflect in losses or improvements in morphological and neuromuscular adaptations related to resistance training. Thus, the aim of the present project is to compare the effects of resistance training performed in the fasted state compared to the fed state during 12 weeks on body composition and physical performance in young adults. Thirty-four eutrophic or overweight individuals, not engaged in regular resistance exercises, aged between 20 and 40 years, will be recruited. They will be put on a standard customized diet and will perform 2 weekly sessions of resistance exercise after overnight fasting (10 to 12 hours) or in the fed state, for 12 weeks. Before, in the middle and after this period, evaluations of body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be analyzed. Comparisons will be performed using Generalized Estimating Equations (GEE), adopting the factors group (2 stratifications) and time (3 stratifications). All results will be expressed as mean and standard deviation and the accepted significance level will be 5%.
Investigators
Eduardo Lusa Cadore
Principal Investigator
Federal University of Rio Grande do Sul
Eligibility Criteria
Inclusion Criteria
- •Men and women;
- •Aged between 19 and 40 years;
- •Body mass index (BMI) between 18 and 29.9 kg/m²;
- •Not engaged in regular strength physical exercise (\>1 weekly session) for the last 3 months.
Exclusion Criteria
- •Use of medications and/or supplements that may influence the outcomes evaluated;
- •Individuals who have a chronic disease that may prevent physical exercise.
Outcomes
Primary Outcomes
Lean body mass
Time Frame: 15 minutes
Lean body mass will be determined using the dual energy X-ray absorption (DEXA) method, using a densitometry machine (Hologic GE, Bedford, USA).
Muscle quality
Time Frame: 30 minutes
Muscle quality will be evaluated through echo intensity of the quadriceps through ultrasound (Nemio XG, Toshiba, Japan).
Body mass
Time Frame: 1 minute
Body mass will be measured using a scale (Urano, Canoas, Brazil).
Maximum dynamic strength
Time Frame: 30 minutes
Maximum dynamic strength will be assessed using the 1 repetition maximum (1RM) test for bench press and knee extension exercises.
Maximum power
Time Frame: 30 minutes
The maximum power and the medium power will be evaluated in the bench press and knee extension exercises considering a load of 30 and 70% of 1RM.
Fat body mass
Time Frame: 15 minutes
Fat body mass will be determined using the dual energy X-ray absorption (DEXA) method, using a densitometry machine (Hologic GE, Bedford, USA).
Muscle thickness
Time Frame: 30 minutes
Muscle thickness will be evaluated through ultrasound (Nemio XG, Toshiba, Japan).