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Clinical Trials/NCT05482750
NCT05482750
Completed
Not Applicable

Effects of Resistance Training Performed in the Fasted State Compared to the Fed State on Morphological and Neuromuscular Adaptations in Young Adults

Federal University of Rio Grande do Sul1 site in 1 country28 target enrollmentMay 23, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Fasting
Sponsor
Federal University of Rio Grande do Sul
Enrollment
28
Locations
1
Primary Endpoint
Lean body mass
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

It is well evidenced in the literature that fasting aerobic exercise generates a series of metabolic differences when compared to exercise performed in the fed state, including the use of fats predominantly as an energy source. Consequently, increases in adaptations to aerobic training, related to health and physical performance, are observed when sessions are performed in the fasted state. In relation to resistance training, the evidence is limited. There is a lack of data in the literature regarding the effects of fasting on resistance exercises and whether this practice may reflect in losses or improvements in morphological and neuromuscular adaptations related to resistance training. Thus, the aim of the present project is to compare the effects of resistance training performed in the fasted state compared to the fed state during 12 weeks on body composition and physical performance in young adults. Thirty-four eutrophic or overweight individuals, not engaged in regular resistance exercises, aged between 20 and 40 years, will be recruited. They will be put on a standard customized diet and will perform 2 weekly sessions of resistance exercise after overnight fasting (10 to 12 hours) or in the fed state, for 12 weeks. Before, in the middle and after this period, evaluations of body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be analyzed. Comparisons will be performed using Generalized Estimating Equations (GEE), adopting the factors group (2 stratifications) and time (3 stratifications). All results will be expressed as mean and standard deviation and the accepted significance level will be 5%.

Registry
clinicaltrials.gov
Start Date
May 23, 2022
End Date
December 23, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Federal University of Rio Grande do Sul
Responsible Party
Principal Investigator
Principal Investigator

Eduardo Lusa Cadore

Principal Investigator

Federal University of Rio Grande do Sul

Eligibility Criteria

Inclusion Criteria

  • Men and women;
  • Aged between 19 and 40 years;
  • Body mass index (BMI) between 18 and 29.9 kg/m²;
  • Not engaged in regular strength physical exercise (\>1 weekly session) for the last 3 months.

Exclusion Criteria

  • Use of medications and/or supplements that may influence the outcomes evaluated;
  • Individuals who have a chronic disease that may prevent physical exercise.

Outcomes

Primary Outcomes

Lean body mass

Time Frame: 15 minutes

Lean body mass will be determined using the dual energy X-ray absorption (DEXA) method, using a densitometry machine (Hologic GE, Bedford, USA).

Muscle quality

Time Frame: 30 minutes

Muscle quality will be evaluated through echo intensity of the quadriceps through ultrasound (Nemio XG, Toshiba, Japan).

Body mass

Time Frame: 1 minute

Body mass will be measured using a scale (Urano, Canoas, Brazil).

Maximum dynamic strength

Time Frame: 30 minutes

Maximum dynamic strength will be assessed using the 1 repetition maximum (1RM) test for bench press and knee extension exercises.

Maximum power

Time Frame: 30 minutes

The maximum power and the medium power will be evaluated in the bench press and knee extension exercises considering a load of 30 and 70% of 1RM.

Fat body mass

Time Frame: 15 minutes

Fat body mass will be determined using the dual energy X-ray absorption (DEXA) method, using a densitometry machine (Hologic GE, Bedford, USA).

Muscle thickness

Time Frame: 30 minutes

Muscle thickness will be evaluated through ultrasound (Nemio XG, Toshiba, Japan).

Study Sites (1)

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