Comparison of two plasma derivates as pulpotomy agents in human immature molars

Phase 1

Not yet recruiting

Conditions: Patients are normal and healthy. Only carious permanent molars will be treated.

Brief Summary: This study is a randomized, split mouth design, single blind trail comparing the efficacy of Platelet Rich Plasma (PRP) and Platelet Rich Fibrin (PRF) as a pulpotomy agent in 25 children 7 to 10 year old with 50 young permanent molars present bilaterally in maxillary or mandibular arch. The study will be conducted in Terna Dental college, Navi mumbai, India. Pulpotomy procedure will be carried out in young permanent molars. The patient will be recalled after 3, 6 and 12 months for clinical and radiographical evaluation. The primary outcome measures will be efficacy of both the materials at 3 months follow up. The secondary outcomes will be efficacy of both the materials as pulpotomy agent at 6 month and 12 month follow up.

Recruitment & Eligibility

Inclusion Criteria

Large carious or mechanical exposure (more than 1 mm) of the vital coronal pulp 2.
Absence of symptoms indicative of advanced pulpal inflammation such as spontaneous pain or history of nocturnal pain 3.
Absence of clinical signs or symptoms suggesting a nonvital tooth such as suppurating sinus, soft tissue swelling.
Restorable tooth structure.
No evidence of external and/or internal root resorption 7.
No widening of periodontal ligament (PDL) space 8.
Absence of furcal or periapical radiolucency 9.
Absence of canal calcification or pulp stone.

Exclusion Criteria

Primary Outcome Measures

Name	Time	Method
Comparison of clinical success of PRP and PRF	3 months

Secondary Outcome Measures

Name	Time	Method
Comparison of clinical and radiographic success of PRP and PRF	6 months and 12 months

Locations (1): Terna Dental College
🇮🇳
(Suburban), MAHARASHTRA, India
Terna Dental College
🇮🇳(Suburban), MAHARASHTRA, India
Dr Devendra Patil
Principal investigator
9930372999
dev1987endra@gmail.com