Incidence of Refeeding Syndrome in Consecutively Admitted Patients

Completed

• Conditions: Refeeding Syndrome; Starvation; Phosphate Deficiency
• Interventions: Other: observation

• Registration Number: NCT05967858
• Lead Sponsor: Jens Rikardt Andersen

Brief Summary

The incidence and main risk-factors analyzed in consecutive in-patients in the departments og gastroenterology and ear-nose and throat diseases (cancer in radiation therapy)

Detailed Description

Patients with either parenteral- or tube feeding enter the study to assure sufficient nutrition.

During hospitalization patients were monitored with daily blood samples and clinical evaluation of symptoms in addition to the coverage of energy and protein in percent of estimated needs.

Refeeding phenomenon was defined as a decrease in plasma phosphate after the initiation of nutrition.

Refeeding syndrome as refeeding phenomenon and one or more relevant symptoms in addition (hypotension, cardiac arrhythmia, edema, confusion)

Study Timeline

• Study Start: 2013-12-01
• Primary Completion: 2014-05-31
• Study Completion: 2023-07-01
• Study First Submitted: 2023-07-21
• Study First Submitted QC: 2023-07-28
• Status Verified: 2023-08
• Study First Posted: 2023-08-01
• Last Update Submitted: 2023-08-09
• Last Update Posted: 2023-08-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 51

Inclusion Criteria

• planned tube- or parenteral nutrition (complete or supplementary)
• > 18 years
• written consent

Exclusion Criteria

• Renal insufficiency (p-creatinine >200 micromol/l)
• Lack of ability to communicate (registration of nutritional intake etc)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
gastroenterological	observation	Consecutive admissions - n= 43 - 34 operated (79%) - 10 patients acutely admitted Diseases in Esophagus (8), gastric cavity (8), pancreas (7), colon/rectum (8), bile (4), small intestine (3), IBD (5) No interventions in the treatments, just observation
head and neck cancer	observation	Consecutive admissions - n=8 - 7 radiation therapy - 1 operated Locations: 2 Larynx, 1 oro-pharynx, 4 tonsillar, 1 tung No interventions in the treatments, just observation

Primary Outcome Measures

Name	Time	Method
Refeeding syndrome	1 week after start of nutrition	No. patients with decrease in plasma phosphate + clinical symptoms

Secondary Outcome Measures

Name	Time	Method
Refeeding phenomenon	1 week after start of nutrition	No. patients with decrease in plasma phosphate after start of nutrition